| Reaction Details |
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 | Report a problem with these data |
| Target | NAD-dependent protein deacetylase |
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| Ligand | BDBM27507 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1822875 (CHEMBL4322639) |
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| IC50 | 23100±n/a nM |
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| Citation |  Monaldi, D; Rotili, D; Lancelot, J; Marek, M; Wössner, N; Lucidi, A; Tomaselli, D; Ramos-Morales, E; Romier, C; Pierce, RJ; Mai, A; Jung, M Structure-Reactivity Relationships on Substrates and Inhibitors of the Lysine Deacylase Sirtuin 2 from J Med Chem62:8733-8759 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| NAD-dependent protein deacetylase |
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| Name: | NAD-dependent protein deacetylase |
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| Synonyms: | 2.3.1.286 | NAD-dependent protein deacetylase | Sirt2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38395.78 |
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| Organism: | Schistosoma mansoni |
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| Description: | ChEMBL_119267 |
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| Residue: | 337 |
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| Sequence: | MSFDFLGIKKALFGDNTPRPELKSLNIEGVAQLIQDGQVNKIITMVGAGVSTAAGIPDFR
SPSSGIYDNLEDFNLPTPNAIFTIDYFRRDPRPFFEIARRLYRPEAKPTLAHCFIRLLHD
KGLLLRHYTQNVDSLERLSGLPEEKLVEAHGTFHTGHCIKCNKQHDFEFMLNEILAKRVP
QCLKCRNVVKPDVVLFGESMPKKFFKNLSSDLNNCDLLIIMGTSLTVLPFCAMIHRVGND
VPRLYINREYNDGSTESGLSSFIMRFMVAGFKQNYMKWGRSDNKRDIFWSGNADDGVVKI
SELLGWKDDLLRLKKETDSRLNEEFLAKKSQDKTNGQ
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| BDBM27507 |
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| n/a |
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| Name | BDBM27507 |
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| Synonyms: | 3-Pyridinecarboxamide | CHEMBL1140 | NAM | niacinamide | nicotinamide | pyridine-3-carboxamide |
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| Type | n/a |
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| Emp. Form. | C6H6N2O |
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| Mol. Mass. | 122.1246 |
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| SMILES | NC(=O)c1cccnc1 |
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| Structure | 
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