| Reaction Details |
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 | Report a problem with these data |
| Target | 5-lipoxygenase |
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| Ligand | BDBM50060899 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_157766 (CHEMBL767669) |
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| IC50 | 8000±n/a nM |
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| Citation |  Müller, K; Prinz, H; Gawlik, I; Ziereis, K; Huang, HS Simple analogues of anthralin: unusual specificity of structure and antiproliferative activity. J Med Chem40:3773-80 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-lipoxygenase |
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| Name: | 5-lipoxygenase |
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| Synonyms: | Arachidonate 5-lipoxygenase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49994.23 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_157766 |
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| Residue: | 430 |
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| Sequence: | MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE
ELGDIQLIKIEKRKYWFHDDWYLKYITVKTPCGDYIEFPCYRWISGEGEIVLRDGQAKLA
CDDQIHVLKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVL
NYSKAMENLFINRFMHMFQSSWSDFADFEKIFVRISNTISERVMNHWQEDRMFGYQFLNG
CNPVMIQRCLKLPDNLPVTTEMVECSLERQLTLEQEIEQGNIFIVDFKLLDGIDANKTDP
CTLQFLAAPICLLYKNLANKIVPIAIQLNQVPGEENPIFLPSDAKYDWLLAKIWVRSSDF
HVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICEYG
LFDKANATGG
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| BDBM50060899 |
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| n/a |
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| Name | BDBM50060899 |
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| Synonyms: | 1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracene-2-carbonitrile | CHEMBL126056 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H9NO3 |
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| Mol. Mass. | 251.2369 |
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| SMILES | Oc1cccc2Cc3ccc(C#N)c(O)c3C(=O)c12 |
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| Structure | 
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