| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serine protease 1 |
|---|
| Ligand | BDBM50076723 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_212522 |
|---|
| Ki | 32000±n/a nM |
|---|
| Citation |  Lee, K; Hwang, SY; Park, CW Thrombin inhibitors based on a propargylglycine template. Bioorg Med Chem Lett9:1013-8 (1999) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Serine protease 1 |
|---|
| Name: | Serine protease 1 |
|---|
| Synonyms: | Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 25790.52 |
|---|
| Organism: | Bos taurus (bovine) |
|---|
| Description: | P00760 |
|---|
| Residue: | 246 |
|---|
| Sequence: | MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVS
AAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLN
SRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQIT
SNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIK
QTIASN
|
|
|
|---|
| BDBM50076723 |
|---|
| n/a |
|---|
| Name | BDBM50076723 |
|---|
| Synonyms: | (S)-5-(3-Amino-4-methylamino-phenyl)-2-(naphthalene-2-sulfonylamino)-pent-4-ynoic acid cyclopentyl-methyl-amide | CHEMBL7124 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C28H32N4O3S |
|---|
| Mol. Mass. | 504.644 |
|---|
| SMILES | CNc1ccc(cc1N)C#CC[C@H](NS(=O)(=O)c1ccc2ccccc2c1)C(=O)N(C)C1CCCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
