| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 14 |
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| Ligand | BDBM50523511 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1890517 (CHEMBL4392271) |
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| IC50 | >3000±n/a nM |
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| Citation |  Junker, A; Renn, C; Dobelmann, C; Namasivayam, V; Jain, S; Losenkova, K; Irjala, H; Duca, S; Balasubramanian, R; Chakraborty, S; Börgel, F; Zimmermann, H; Yegutkin, GG; Müller, CE; Jacobson, KA Structure-Activity Relationship of Purine and Pyrimidine Nucleotides as Ecto-5'-Nucleotidase (CD73) Inhibitors. J Med Chem62:3677-3695 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 14 |
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| Name: | P2Y purinoceptor 14 |
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| Synonyms: | GPR105 | Insulin Receptor-Related Protein (INSRR) | KIAA0001 | P2RY14 | P2Y14_HUMAN | Purinergic receptor P2Y14 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38991.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1502487 |
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| Residue: | 338 |
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| Sequence: | MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYL
KNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRY
YKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELG
RKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVF
VFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQ
PFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL
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| BDBM50523511 |
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| n/a |
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| Name | BDBM50523511 |
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| Synonyms: | CHEMBL4443977 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H25N3O11P2 |
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| Mol. Mass. | 521.3521 |
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| SMILES | Cn1c(=O)n(cc\c1=N/OCc1ccccc1)[C@@H]1O[C@H](COP(O)(=O)CP(O)(O)=O)[C@@H](O)[C@H]1O |r| |
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| Structure | 
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