| Reaction Details |
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 | Report a problem with these data |
| Target | Kallikrein-14 |
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| Ligand | BDBM50525900 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1898431 (CHEMBL4400466) |
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| IC50 | 398±n/a nM |
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| Citation |  Walker, AL; Denis, A; Bingham, RP; Bouillot, A; Edgar, EV; Ferrie, A; Holmes, DS; Laroze, A; Liddle, J; Fouchet, MH; Moquette, A; Nassau, P; Pearce, AC; Polyakova, O; Smith, KJ; Thomas, P; Thorpe, JH; Trottet, L; Wang, Y; Hovnanian, A Design and development of a series of borocycles as selective, covalent kallikrein 5 inhibitors. Bioorg Med Chem Lett29:0 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kallikrein-14 |
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| Name: | Kallikrein-14 |
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| Synonyms: | KLK-L6 | KLK14 | KLK14_HUMAN | KLKL6 | Kallikrein 14 | Kallikrein-14 | Kallikrein-like protein 6 | hK14 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 29136.99 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1282452 |
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| Residue: | 267 |
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| Sequence: | MSLRVLGSGTWPSAPKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLA
GPRRRFLCGGALLSGQWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYN
SRTHDNDLMLLQLQQPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQC
VNINISPDEVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMER
CALPGYPGVYTNLCKYRSWIEETMRDK
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| BDBM50525900 |
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| n/a |
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| Name | BDBM50525900 |
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| Synonyms: | CHEMBL4460168 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H23BClN3O3 |
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| Mol. Mass. | 423.7 |
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| SMILES | Cl.Cc1cccc2CC(OB(O)c12)c1ccc(C(N)=N)c(OCc2cccnc2)c1 |
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| Structure | 
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