| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Growth factor receptor-bound protein 2 |
|---|
| Ligand | BDBM50082258 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_67053 |
|---|
| IC50 | 18200±n/a nM |
|---|
| Citation |  García-Echeverría, C; Gay, B; Rahuel, J; Furet, P Mapping the X(+1) binding site of the Grb2-SH2 domain with alpha,alpha-disubstituted cyclic alpha-amino acids. Bioorg Med Chem Lett9:2915-20 (1999) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Growth factor receptor-bound protein 2 |
|---|
| Name: | Growth factor receptor-bound protein 2 |
|---|
| Synonyms: | ASH | GRB2 | GRB2 adapter protein | GRB2_HUMAN | Grb2-SH2 | Growth factor receptor-bound protein 2 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 25205.04 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P62993 |
|---|
| Residue: | 217 |
|---|
| Sequence: | MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
|
|
|
|---|
| BDBM50082258 |
|---|
| n/a |
|---|
| Name | BDBM50082258 |
|---|
| Synonyms: | CHEMBL2370326 | Phosphoric acid mono-(4-{acetylamino-[1-(1,2-dicarbamoyl-ethylcarbamoyl)-cyclobutylcarbamoyl]-methyl}-phenyl) ester |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H26N5O9P |
|---|
| Mol. Mass. | 499.4116 |
|---|
| SMILES | CC(=O)N[C@H](C(=O)NC1(CCC1)C(=O)N[C@@H](CC(N)=O)C(N)=O)c1ccc(OP(O)(O)=O)cc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
