Reaction Details |
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Target | Chymotrypsinogen A |
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Ligand | BDBM50085355 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_215994 |
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IC50 | 18000±n/a nM |
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Citation | Hayashi, Y; Iijima, K; Katada, J; Kiso, Y Structure-activity relationship studies of chloromethyl ketone derivatives for selective human chymase inhibitors. Bioorg Med Chem Lett10:199-201 (2000) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Chymotrypsinogen A |
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Name: | Chymotrypsinogen A |
Synonyms: | Alpha-chymotrypsin | CTRA_BOVIN | Chymotrypsin A | Chymotrypsin A chain A | Chymotrypsin A chain B | Chymotrypsin A chain C | Chymotrypsinogen A | alpha-Chymotrypsin (α-Chymotrypsin) |
Type: | Serine protease |
Mol. Mass.: | 25670.88 |
Organism: | Bos taurus (bovine) |
Description: | n/a |
Residue: | 245 |
Sequence: | CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGV
TTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSA
VCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAM
ICAGASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQ
TLAAN
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BDBM50085355 |
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n/a |
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Name | BDBM50085355 |
Synonyms: | CHEMBL60080 | N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(4-chloro-phenyl)-propionamide |
Type | Small organic molecule |
Emp. Form. | C19H19Cl2NO2 |
Mol. Mass. | 364.266 |
SMILES | ClCC(=O)[C@H](Cc1ccccc1)NC(=O)CCc1ccc(Cl)cc1 |
Structure |
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