| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50534214 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1927920 (CHEMBL4430992) |
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| Ki | >1000±n/a nM |
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| Citation |  Brunschweiger, A; Koch, P; Schlenk, M; Rafehi, M; Radjainia, H; Küppers, P; Hinz, S; Pineda, F; Wiese, M; Hockemeyer, J; Heer, J; Denonne, F; Müller, CE 8-Substituted 1,3-dimethyltetrahydropyrazino[2,1-f]purinediones: Water-soluble adenosine receptor antagonists and monoamine oxidase B inhibitors. Bioorg Med Chem24:5462-5480 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50534214 |
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| n/a |
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| Name | BDBM50534214 |
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| Synonyms: | CHEMBL4471953 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20FN5O3 |
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| Mol. Mass. | 373.3815 |
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| SMILES | Cn1c2nc3CN(CCOc4ccccc4F)CCn3c2c(=O)n(C)c1=O |
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| Structure | 
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