| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 6 |
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| Ligand | BDBM50090524 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_3623 |
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| Ki | 13±n/a nM |
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| Citation |  Isaac, M; Slassi, A; Xin, T; MacLean, N; Wilson, J; McCallum, K; Wang, H; Demchyshyn, L 6-Bicyclopiperazinyl-1-arylsulfonylindoles and 6-bicyclopiperidinyl-1-arylsulfonylindoles derivatives as novel, potent, and selective 5-HT6 receptor antagonists. Bioorg Med Chem Lett10:1719-21 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 6 |
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| Name: | 5-hydroxytryptamine receptor 6 |
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| Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 46968.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P50406 |
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| Residue: | 440 |
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| Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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| BDBM50090524 |
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| n/a |
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| Name | BDBM50090524 |
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| Synonyms: | 4-Amino-N-(2,6-bis-methylamino-pyridin-4-yl)-benzenesulfonamide | 4-Amino-N-(2,6-diamino-pyridin-4-yl)-benzenesulfonamide | 4-Amino-N-(2-methylamino-pyridin-4-yl)-benzenesulfonamide | CHEMBL46071 | N-(2,6-bis(methylamino)pyridin-4-yl)-4-aminobenzenesulfonamide | Ro-63-0563 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H17N5O2S |
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| Mol. Mass. | 307.371 |
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| SMILES | CNc1cc(NS(=O)(=O)c2ccc(N)cc2)cc(NC)n1 |
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| Structure | 
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