| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-Y |
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| Ligand | BDBM50535581 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1930925 (CHEMBL4434176) |
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| IC50 | 3.4±n/a nM |
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| Citation |  Ferguson, FM; Doctor, ZM; Ficarro, SB; Marto, JA; Kim, ND; Sim, T; Gray, NS Synthesis and structure activity relationships of a series of 4-amino-1H-pyrazoles as covalent inhibitors of CDK14. Bioorg Med Chem Lett29:1985-1993 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cyclin-Y |
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| Name: | Cyclin-Y |
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| Synonyms: | C10orf9 | CBCP1 | CCNY | CCNY_HUMAN | CFP1 | Cyc-Y | Cyclin box protein 1 | Cyclin fold protein 1 | Cyclin-Y | cyclin-X |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39339.72 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_118346 |
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| Residue: | 341 |
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| Sequence: | MGNTTSCCVSSSPKLRRNAHSRLESYRPDTDLSREDTGCNLQHISDRENIDDLNMEFNPS
DHPRASTIFLSKSQTDVREKRKSLFINHHPPGQIARKYSSCSTIFLDDSTVSQPNLKYTI
KCVALAIYYHIKNRDPDGRMLLDIFDENLHPLSKSEVPPDYDKHNPEQKQIYRFVRTLFS
AAQLTAECAIVTLVYLERLLTYAEIDICPANWKRIVLGAILLASKVWDDQAVWNVDYCQI
LKDITVEDMNELERQFLELLQFNINVPSSVYAKYYFDLRSLAEANNLSFPLEPLSRERAH
KLEAISRLCEDKYKDLRRSARKRSASADNLTLPRWSPAIIS
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| BDBM50535581 |
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| n/a |
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| Name | BDBM50535581 |
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| Synonyms: | CHEMBL4527767 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H32F5N7O7S |
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| Mol. Mass. | 729.675 |
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| SMILES | OC(=O)C(F)(F)F.CN(C)C\C=C\C(=O)Nc1cccc(c1)S(=O)(=O)N1CCC(CC1)NC(=O)c1n[nH]cc1NC(=O)c1c(F)cccc1F |
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| Structure | 
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