| Reaction Details |
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 | Report a problem with these data |
| Target | Platelet glycoprotein VI |
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| Ligand | BDBM50016900 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2033130 (CHEMBL4687288) |
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| IC50 | 35000±n/a nM |
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| Citation |  Foster, H; Wilson, C; Philippou, H; Foster, R Progress toward a Glycoprotein VI Modulator for the Treatment of Thrombosis. J Med Chem63:12213-12242 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Platelet glycoprotein VI |
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| Name: | Platelet glycoprotein VI |
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| Synonyms: | GP6 | GPVI | GPVI_HUMAN | Glycoprotein 6 | Platelet glycoprotein VI |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36878.67 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109099 |
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| Residue: | 339 |
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| Sequence: | MSPSPTALFCLGLCLGRVPAQSGPLPKPSLQALPSSLVPLEKPVTLRCQGPPGVDLYRLE
KLSSSRYQDQAVLFIPAMKRSLAGRYRCSYQNGSLWSLPSDQLELVATGVFAKPSLSAQP
GPAVSSGGDVTLQCQTRYGFDQFALYKEGDPAPYKNPERWYRASFPIITVTAAHSGTYRC
YSFSSRDPYLWSAPSDPLELVVTGTSVTPSRLPTEPPSPVAEFSEATAELTVSFTNEVFT
TETSRSITASPKESDSPAGPARQYYTKGNLVRICLGAVILIILAGFLAEDWHSRRKRLRH
RGRAVQRPLPPLPPLPLTRKSNGGQDGGRQDVHSRGLCS
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| BDBM50016900 |
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| n/a |
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| Name | BDBM50016900 |
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| Synonyms: | (E)-N-[2-(3-Dimethylamino-propylsulfanyl)-phenyl]-3-phenyl-acrylamide | CHEMBL18786 | CINANSERIN | N-(2-(3-(dimethylamino)propylthio)phenyl)cinnamamide | N-[2-(3-Dimethylamino-propylsulfanyl)-phenyl]-3-phenyl-acrylamide | N-[2-(3-Dimethylamino-propylsulfanyl)-phenyl]-3-phenyl-acrylamide (cinanserin) | N-[2-(3-Dimethylamino-propylsulfanyl)-phenyl]-3-phenyl-acrylamide(Cinanserin) | acs.jmedchem.1c00409_ST.370 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24N2OS |
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| Mol. Mass. | 340.482 |
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| SMILES | CN(C)CCCSc1ccccc1NC(=O)\C=C\c1ccccc1 |
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| Structure | 
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