| Reaction Details |
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 | Report a problem with these data |
| Target | Platelet glycoprotein VI |
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| Ligand | BDBM250082 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2033139 (CHEMBL4687297) |
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| IC50 | 510±n/a nM |
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| Citation |  Foster, H; Wilson, C; Philippou, H; Foster, R Progress toward a Glycoprotein VI Modulator for the Treatment of Thrombosis. J Med Chem63:12213-12242 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Platelet glycoprotein VI |
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| Name: | Platelet glycoprotein VI |
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| Synonyms: | GP6 | GPVI | GPVI_HUMAN | Glycoprotein 6 | Platelet glycoprotein VI |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36878.67 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109099 |
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| Residue: | 339 |
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| Sequence: | MSPSPTALFCLGLCLGRVPAQSGPLPKPSLQALPSSLVPLEKPVTLRCQGPPGVDLYRLE
KLSSSRYQDQAVLFIPAMKRSLAGRYRCSYQNGSLWSLPSDQLELVATGVFAKPSLSAQP
GPAVSSGGDVTLQCQTRYGFDQFALYKEGDPAPYKNPERWYRASFPIITVTAAHSGTYRC
YSFSSRDPYLWSAPSDPLELVVTGTSVTPSRLPTEPPSPVAEFSEATAELTVSFTNEVFT
TETSRSITASPKESDSPAGPARQYYTKGNLVRICLGAVILIILAGFLAEDWHSRRKRLRH
RGRAVQRPLPPLPPLPLTRKSNGGQDGGRQDVHSRGLCS
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| BDBM250082 |
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| n/a |
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| Name | BDBM250082 |
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| Synonyms: | US9447106, 27b (peak 2) | US9556188, Compound 27a |
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| Type | Small organic molecule |
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| Emp. Form. | C27H29N5O3 |
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| Mol. Mass. | 471.5509 |
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| SMILES | NC(=O)c1c2NCC[C@@H](C3CCN(CC3)C(=O)C=C)n2nc1-c1ccc(Oc2ccccc2)cc1 |r| |
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| Structure | 
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