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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Mitogen-activated protein kinase 6 | ||
| Ligand | BDBM50553816 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_2047485 (CHEMBL4702184) | ||
| Kd | 2200±n/a nM | ||
| Citation |  Grädler, U; Busch, M; Leuthner, B; Raba, M; Burgdorf, L; Lehmann, M; Linde, N; Esdar, C Biochemical, cellular and structural characterization of novel and selective ERK3 inhibitors. Bioorg Med Chem Lett30:0 (2020) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Mitogen-activated protein kinase 6 | |||
| Name: | Mitogen-activated protein kinase 6 | ||
| Synonyms: | ERK3 | MAPK6 | MK06_HUMAN | PRKM6 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 82643.07 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_774367 | ||
| Residue: | 721 | ||
| Sequence: |
| ||
| BDBM50553816 | |||
| n/a | |||
| Name | BDBM50553816 | ||
| Synonyms: | CHEMBL4784697 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C18H23N7O | ||
| Mol. Mass. | 353.4215 | ||
| SMILES | COc1ccc(cc1)-n1nnc2cnc(N[C@H]3CC[C@H](CN)CC3)nc12 |r,wU:19.20,wD:16.16,(33.12,-45.27,;31.61,-45.6,;31.15,-47.06,;32.19,-48.2,;31.72,-49.67,;30.21,-49.99,;29.18,-48.86,;29.64,-47.4,;29.75,-51.45,;30.66,-52.7,;29.76,-53.95,;28.29,-53.48,;26.95,-54.26,;25.62,-53.49,;25.62,-51.95,;24.29,-51.18,;24.29,-49.64,;25.62,-48.87,;25.63,-47.34,;24.3,-46.56,;24.3,-45.02,;25.64,-44.26,;22.96,-47.33,;22.95,-48.87,;26.95,-51.18,;28.28,-51.94,)| | ||
| Structure | 
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