| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-O |
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| Ligand | BDBM50563174 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2081665 (CHEMBL4737456) |
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| IC50 | 33±n/a nM |
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| Citation |  Lee, JC; Hong, KH; Becker, A; Tash, JS; Schönbrunn, E; Georg, GI Tetrahydroindazole inhibitors of CDK2/cyclin complexes. Eur J Med Chem214:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Cyclin-O |
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| Name: | Cyclin-O |
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| Synonyms: | CCNO | CCNO_HUMAN | CDK2/Cyclin O | Cyclin-O |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38106.14 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_117722 |
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| Residue: | 350 |
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| Sequence: | MVTPCPTSPSSPAARAGRRDNDQNLRAPVKKSRRPRLRRKQPLHPLNPCPLPGDSGICDL
FESPSSGSDGAESPSAARGGSPLPGPAQPVAQLDLQTFRDYGQSCYAFRKAQESHFHPRE
ALARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGV
TSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTLGAPTISFFLEHF
THARVEAGQAEASEALEAQALARGVAELSLADYAFTSYSPSLLAICCLALADRMLRVSRP
VDLRLGDHPEAALEDCMGKLQLLVAINSTSLTHMLPVQICEKCSLPPSSK
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| BDBM50563174 |
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| n/a |
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| Name | BDBM50563174 |
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| Synonyms: | CHEMBL1708376 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H14BrN3OS |
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| Mol. Mass. | 340.239 |
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| SMILES | Cc1nn(-c2nccs2)c2C(Br)C(C)(C)CC(=O)c12 |
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| Structure | 
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