| Reaction Details |
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 | Report a problem with these data |
| Target | REST corepressor 1 |
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| Ligand | BDBM50346863 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2105723 (CHEMBL4814398) |
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| Ki | 1100±n/a nM |
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| Citation |  Dai, XJ; Liu, Y; Xiong, XP; Xue, LP; Zheng, YC; Liu, HM Tranylcypromine Based Lysine-Specific Demethylase 1 Inhibitor: Summary and Perspective. J Med Chem63:14197-14215 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| REST corepressor 1 |
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| Name: | REST corepressor 1 |
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| Synonyms: | KIAA0071 | Protein CoREST | RCOR | RCOR1 | RCOR1_HUMAN | REST corepressor 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53329.34 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_108118 |
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| Residue: | 485 |
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| Sequence: | MPAMVEKGPEVSGKRRGRNNAAASASAAAASAAASAACASPAATAASGAAASSASAAAAS
AAAAPNNGQNKSLAAAAPNGNSSSNSWEEGSSGSSSDEEHGGGGMRVGPQYQAVVPDFDP
AKLARRSQERDNLGMLVWSPNQNLSEAKLDEYIAIAKEKHGYNMEQALGMLFWHKHNIEK
SLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTR
TKTSVMDRHARKQKREREESEDELEEANGNNPIDIEVDQNKESKKEVPPTETVPQVKKEK
HSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNS
ALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQV
KNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQKPVKSPDNSIKMPEEEDEAPVLDVR
YASAS
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| BDBM50346863 |
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| n/a |
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| Name | BDBM50346863 |
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| Synonyms: | CHEMBL1797640 | US8765820, 5b |
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| Type | Small organic molecule |
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| Emp. Form. | C16H16N2O |
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| Mol. Mass. | 252.311 |
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| SMILES | NC1CC1c1ccc(NC(=O)c2ccccc2)cc1 |
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| Structure | 
|
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