| Reaction Details |
|---|
 | Report a problem with these data |
| Target | REST corepressor 1 |
|---|
| Ligand | BDBM50568523 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2105758 (CHEMBL4814433) |
|---|
| IC50 | 2.1±n/a nM |
|---|
| Citation |  Dai, XJ; Liu, Y; Xiong, XP; Xue, LP; Zheng, YC; Liu, HM Tranylcypromine Based Lysine-Specific Demethylase 1 Inhibitor: Summary and Perspective. J Med Chem63:14197-14215 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| REST corepressor 1 |
|---|
| Name: | REST corepressor 1 |
|---|
| Synonyms: | KIAA0071 | Protein CoREST | RCOR | RCOR1 | RCOR1_HUMAN | REST corepressor 1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 53329.34 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_108118 |
|---|
| Residue: | 485 |
|---|
| Sequence: | MPAMVEKGPEVSGKRRGRNNAAASASAAAASAAASAACASPAATAASGAAASSASAAAAS
AAAAPNNGQNKSLAAAAPNGNSSSNSWEEGSSGSSSDEEHGGGGMRVGPQYQAVVPDFDP
AKLARRSQERDNLGMLVWSPNQNLSEAKLDEYIAIAKEKHGYNMEQALGMLFWHKHNIEK
SLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTR
TKTSVMDRHARKQKREREESEDELEEANGNNPIDIEVDQNKESKKEVPPTETVPQVKKEK
HSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNS
ALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQV
KNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQKPVKSPDNSIKMPEEEDEAPVLDVR
YASAS
|
|
|
|---|
| BDBM50568523 |
|---|
| n/a |
|---|
| Name | BDBM50568523 |
|---|
| Synonyms: | CHEMBL4875015 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H23ClN4O |
|---|
| Mol. Mass. | 346.854 |
|---|
| SMILES | Cl.Cn1cc(cn1)C(=O)Nc1ccc(cc1)[C@@H]1C[C@H]1NCC1CC1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
