| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mucolipin-3 |
|---|
| Ligand | BDBM50569852 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2110660 (CHEMBL4819510) |
|---|
| IC50 | >100000±n/a nM |
|---|
| Citation |  Leser, C; Keller, M; Gerndt, S; Urban, N; Chen, CC; Schaefer, M; Grimm, C; Bracher, F Chemical and pharmacological characterization of the TRPML calcium channel blockers ML-SI1 and ML-SI3. Eur J Med Chem210:0 (2021) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Mucolipin-3 |
|---|
| Name: | Mucolipin-3 |
|---|
| Synonyms: | MCLN3_HUMAN | MCOLN3 | MCOLN3 protein |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 64244.09 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q8TDD5 |
|---|
| Residue: | 553 |
|---|
| Sequence: | MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKP
WKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQS
DVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPE
IETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYD
FTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSL
ILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKM
EIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAA
MIYLGYCFCGWIVLGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRI
YLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLPNSGKYRLE
DDPPVSLFCCCKK
|
|
|
|---|
| BDBM50569852 |
|---|
| n/a |
|---|
| Name | BDBM50569852 |
|---|
| Synonyms: | CHEMBL4856325 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H27N3O2S |
|---|
| Mol. Mass. | 337.48 |
|---|
| SMILES | CN1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
