| Reaction Details |
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 | Report a problem with these data |
| Target | Procathepsin L |
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| Ligand | BDBM50573801 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2120724 (CHEMBL4829871) |
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| IC50 | >10000±n/a nM |
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| Citation |  Chen, X; Yan, Y; Zhang, Z; Zhang, F; Liu, M; Du, L; Zhang, H; Shen, X; Zhao, D; Shi, JB; Liu, X Discovery and J Med Chem64:11857-11885 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Procathepsin L |
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| Name: | Procathepsin L |
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| Synonyms: | CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein |
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| Type: | Enzyme |
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| Mol. Mass.: | 37557.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Purchased from Calbiochem (San Diego, CA). |
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| Residue: | 333 |
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| Sequence: | MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
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| BDBM50573801 |
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| n/a |
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| Name | BDBM50573801 |
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| Synonyms: | CHEMBL4859234 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H21ClF3N7 |
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| Mol. Mass. | 463.887 |
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| SMILES | CN1CCN(CC1)c1ccc(Nc2ncc(Cl)c(Nc3cccc(c3)C(F)(F)F)n2)nc1 |
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| Structure | 
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