Reaction Details |
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Target | 5-hydroxytryptamine receptor 6 |
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Ligand | BDBM50582608 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_2155124 (CHEMBL5039784) |
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Ki | >10000±n/a nM |
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Citation | Lee, J; Kwag, R; Lee, S; Kim, D; Woo, J; Cho, Y; Kim, HJ; Kim, J; Jeon, B; Choo, H Discovery of G Protein-Biased Ligands against 5-HT J Med Chem64:7453-7467 (2021) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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5-hydroxytryptamine receptor 6 |
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Name: | 5-hydroxytryptamine receptor 6 |
Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 46968.43 |
Organism: | Homo sapiens (Human) |
Description: | P50406 |
Residue: | 440 |
Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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BDBM50582608 |
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n/a |
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Name | BDBM50582608 |
Synonyms: | CHEMBL5084249 |
Type | Small organic molecule |
Emp. Form. | C19H24ClNO |
Mol. Mass. | 317.853 |
SMILES | CCN(CC)CCc1ccc(Cl)c(c1)-c1ccccc1OC |
Structure |
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