Citation | Chen, C; Wilcoxen, KM; Huang, CQ; Xie, YF; McCarthy, JR; Webb, TR; Zhu, YF; Saunders, J; Liu, XJ; Chen, TK; Bozigian, H; Grigoriadis, DE Design of 2,5-dimethyl-3-(6-dimethyl-4-methylpyridin-3-yl)-7-dipropylaminopyrazolo[1,5-a]pyrimidine (NBI 30775/R121919) and structure--activity relationships of a series of potent and orally active corticotropin-releasing factor receptor antagonists. J Med Chem47:4787-98 (2004) [PubMed] Article |
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SMILES | CCCN(c1ccccc1)c1cc(C)nc2c(c(C)nn12)-c1cnc(cc1C)N(C)C |(7.25,-.89,;5.74,-.59,;5.25,.88,;3.76,1.18,;3.27,2.65,;4.29,3.79,;3.81,5.24,;2.31,5.56,;1.29,4.4,;1.76,2.95,;2.73,.04,;3.2,-1.42,;2.17,-2.57,;2.66,-4.03,;.68,-2.24,;.19,-.8,;-1.2,-.17,;-1.04,1.35,;-2.21,2.37,;.45,1.68,;1.22,.34,;-2.53,-.96,;-2.53,-2.5,;-3.86,-3.27,;-5.19,-2.5,;-5.19,-.96,;-3.86,-.17,;-3.86,1.35,;-6.52,-3.27,;-6.52,-4.81,;-7.84,-2.5,)| |