| Reaction Details |
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 | Report a problem with these data |
| Target | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta |
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| Ligand | BDBM50583526 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2157652 (CHEMBL5042312) |
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| Ki | 49±n/a nM |
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| Citation |  Guo, M; He, S; Cheng, J; Li, Y; Dong, G; Sheng, C Hydrophobic Tagging-Induced Degradation of PDE? in Colon Cancer Cells. ACS Med Chem Lett13:298-303 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta |
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| Name: | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta |
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| Synonyms: | 3',5'-cyclic phosphodiesterase | GMP-PDE delta | PDE6D | PDE6D_HUMAN | PDED | Protein p17 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta |
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| Type: | PROTEIN |
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| Mol. Mass.: | 17418.30 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_105761 |
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| Residue: | 150 |
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| Sequence: | MSAKDERAREILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVS
RELNFSSTEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPA
SVLTGNVIIETKFFDDDLLVSTSRVRLFYV
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| BDBM50583526 |
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| n/a |
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| Name | BDBM50583526 |
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| Synonyms: | CHEMBL5072868 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H46N6O3 |
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| Mol. Mass. | 586.7674 |
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| SMILES | Cc1n(nc2c1c(C)nn(CCCC(=O)NCCCCNC(=O)CC13CC4CC(CC(C4)C1)C3)c2=O)-c1ccc(C)cc1 |TLB:27:28:25.26.31:32,THB:27:26:33.28.29:32,29:28:25:31.30.32,29:30:25:33.28.27| |
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| Structure | 
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