| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 14 |
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| Ligand | BDBM50584884 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2160851 (CHEMBL5045601) |
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| IC50 | 64.1±n/a nM |
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| Citation |  Wen, Z; Salmaso, V; Jung, YH; Phung, NB; Gopinatth, V; Shah, Q; Patterson, AT; Randle, JCR; Chen, Z; Salvemini, D; Lieberman, DI; Whitehead, GS; Karcz, TP; Cook, DN; Jacobson, KA Bridged Piperidine Analogues of a High Affinity Naphthalene-Based P2Y J Med Chem65:3434-3459 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 14 |
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| Name: | P2Y purinoceptor 14 |
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| Synonyms: | GPR105 | Insulin Receptor-Related Protein (INSRR) | KIAA0001 | P2RY14 | P2Y14_HUMAN | Purinergic receptor P2Y14 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38991.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1502487 |
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| Residue: | 338 |
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| Sequence: | MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYL
KNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRY
YKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELG
RKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVF
VFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQ
PFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL
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| BDBM50584884 |
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| n/a |
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| Name | BDBM50584884 |
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| Synonyms: | CHEMBL5075741 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H26F3NO3 |
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| Mol. Mass. | 529.5489 |
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| SMILES | [H][C@]12CN(C(C)=O)[C@]([H])(C[C@H]1c1ccc(cc1)-c1cc(cc3cc(ccc13)-c1ccc(cc1)C(F)(F)F)C(O)=O)C2 |r| |
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| Structure | 
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