| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Transporter |
|---|
| Ligand | BDBM50155451 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_303591 (CHEMBL829602) |
|---|
| Ki | 2.03±n/a nM |
|---|
| Citation |  Peng, X; Zhang, A; Kula, NS; Baldessarini, RJ; Neumeyer, JL Synthesis and amine transporter affinities of novel phenyltropane derivatives as potential positron emission tomography (PET) imaging agents. Bioorg Med Chem Lett14:5635-9 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Transporter |
|---|
| Name: | Transporter |
|---|
| Synonyms: | Monoamine transporters; Norepininephrine & dopamine | Norepinephrine Monoamine transporters |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 66787.87 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_1463061 |
|---|
| Residue: | 597 |
|---|
| Sequence: | MVTRTRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLF
YMELALGQFNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLN
LPWTNCGHAWNSPNCTDPKLLNASVLGDHTKYSKYKFTPAAEFYERGVLHLHESSGIHDI
GLPQWQLLLCLMVVIVVLYVSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNG
INAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTIN
CVTSFISGFAIFSILGYMAHEHKVKIEDVATEGAGLVFVLYPEAISTLSGSTFWAVLFFL
MLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCAVTLGTFLLAMFCITKGGIYVLT
LLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLL
FVVVVSIINFKPLTYDDYVYPPWANWVGWGIALSSMILVPAYVIYKFFSIRGSLWERVAY
GITPENEHHLLALEIELSSLQSFVITSCPIDPLLSSFLFISCQKTLVFKKSGPAPLI
|
|
|
|---|
| BDBM50155451 |
|---|
| n/a |
|---|
| Name | BDBM50155451 |
|---|
| Synonyms: | 3-(4-Bromo-phenyl)-8-(3-fluoro-propyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid 2-fluoro-ethyl ester | CHEMBL184123 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H24BrF2NO2 |
|---|
| Mol. Mass. | 416.3 |
|---|
| SMILES | FCCCN1C2CCC1C(C(C2)c1ccc(Br)cc1)C(=O)OCCF |TLB:19:9:4:7.6,3:4:9.10.11:7.6,THB:12:10:4:7.6| |
|---|
| Structure | 
|
|---|
Search and Browse
