| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase pim-1 |
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| Ligand | BDBM50593646 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2209415 (CHEMBL5122364) |
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| IC50 | 770±n/a nM |
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| Citation |  Singh, H; Agrawal, DK Recent advances in the development of active hybrid molecules in the treatment of cardiovascular diseases. Bioorg Med Chem62:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase pim-1 |
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| Name: | Serine/threonine-protein kinase pim-1 |
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| Synonyms: | PIM-1 Kinase | PIM1 | PIM1_HUMAN | Proto-oncogene serine/threonine-protein kinase Pim-1 | Serine/threonine-protein kinase (PIM1) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase PIM1 | Serine/threonine-protein kinase pim-1 (PIM1) |
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| Type: | Protein |
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| Mol. Mass.: | 35681.82 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P11309 |
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| Residue: | 313 |
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| Sequence: | MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSD
NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLIL
ERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRG
ELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDI
PFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETA
EIHLHSLSPGPSK
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| BDBM50593646 |
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| n/a |
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| Name | BDBM50593646 |
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| Synonyms: | CHEMBL5198672 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H8BrN3O2S2 |
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| Mol. Mass. | 370.245 |
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| SMILES | CN1C(=O)\C(=C2\SC(=S)N(N)C2=O)c2cc(Br)ccc12 |
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| Structure | 
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