| Reaction Details |
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 | Report a problem with these data |
| Target | Cysteinyl leukotriene receptor 2 |
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| Ligand | BDBM50596196 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2219724 (CHEMBL5133058) |
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| EC50 | 8.9±n/a nM |
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| Citation |  Fiorillo, B; Sepe, V; Conflitti, P; Roselli, R; Biagioli, M; Marchianò, S; De Luca, P; Baronissi, G; Rapacciuolo, P; Cassiano, C; Catalanotti, B; Zampella, A; Limongelli, V; Fiorucci, S Structural Basis for Developing Multitarget Compounds Acting on Cysteinyl Leukotriene Receptor 1 and G-Protein-Coupled Bile Acid Receptor 1. J Med Chem64:16512-16529 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cysteinyl leukotriene receptor 2 |
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| Name: | Cysteinyl leukotriene receptor 2 |
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| Synonyms: | CLTR2_HUMAN | CYSLT2 | CYSLT2R | CYSLTR2 | Cysteinyl leukotriene receptor | Cysteinyl leukotriene receptor 2 | Leukotriene Cysteinyl 2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 39657.52 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Leukotriene Cysteinyl 2 CYSLTR2 HUMAN::Q9NS75 |
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| Residue: | 346 |
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| Sequence: | MERKFMSLQPSISVSEMEPNGTFSNNNSRNCTIENFKREFFPIVYLIIFFWGVLGNGLSI
YVFLQPYKKSTSVNVFMLNLAISDLLFISTLPFRADYYLRGSNWIFGDLACRIMSYSLYV
NMYSSIYFLTVLSVVRFLAMVHPFRLLHVTSIRSAWILCGIIWILIMASSIMLLDSGSEQ
NGSVTSCLELNLYKIAKLQTMNYIALVVGCLLPFFTLSICYLLIIRVLLKVEVPESGLRV
SHRKALTTIIITLIIFFLCFLPYHTLRTVHLTTWKVGLCKDRLHKALVITLALAAANACF
NPLLYYFAGENFKDRLKSALRKGHPQKAKTKCVFPVSVWLRKETRV
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| BDBM50596196 |
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| n/a |
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| Name | BDBM50596196 |
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| Synonyms: | CHEBI:16978 | CHEMBL451509 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H47N3O9S |
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| Mol. Mass. | 625.774 |
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| SMILES | CCCCC\C=C/C\C=C/C=C/C=C/[C@@H](SC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)[C@@H](O)CCCC(O)=O |r| |
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| Structure | 
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