| Reaction Details |
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 | Report a problem with these data |
| Target | Inositol hexakisphosphate kinase 1 |
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| Ligand | BDBM50605495 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2251834 (CHEMBL5166044) |
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| IC50 | 430±n/a nM |
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| Citation |  Zhou, Y; Mukherjee, S; Huang, D; Chakraborty, M; Gu, C; Zong, G; Stashko, MA; Pearce, KH; Shears, SB; Chakraborty, A; Wang, H; Wang, X Development of Novel IP6K Inhibitors for the Treatment of Obesity and Obesity-Induced Metabolic Dysfunctions. J Med Chem65:6869-6887 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Inositol hexakisphosphate kinase 1 |
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| Name: | Inositol hexakisphosphate kinase 1 |
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| Synonyms: | 2.7.4.21 | IHPK1 | IP6K1 | IP6K1_HUMAN | Inositol hexakisphosphate kinase 1 | Inositol hexaphosphate kinase 1 | InsP6 kinase 1 | KIAA0263 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50242.08 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_119168 |
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| Residue: | 441 |
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| Sequence: | MCVCQTMEVGQYGKNASRAGDRGVLLEPFIHQVGGHSSMMRYDDHTVCKPLISREQRFYE
SLPPEMKEFTPEYKGVVSVCFEGDSDGYINLVAYPYVESETVEQDDTTEREQPRRKHSRR
SLHRSGSGSDHKEEKASLSLETSESSQEAKSPKVELHSHSEVPFQMLDGNSGLSSEKISH
NPWSLRCHKQQLSRMRSESKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEK
AARQMRKCEQSTSATLGVRVCGMQVYQLDTGHYLCRNKYYGRGLSIEGFRNALYQYLHNG
LDLRRDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECRAESCLDRRSEMRLKH
LDMVLPEVASSCGPSTSPSNTSPEAGPSSQPKVDVRMIDFAHSTFKGFRDDPTVHDGPDR
GYVFGLENLISIMEQMRDENQ
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| BDBM50605495 |
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| n/a |
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| Name | BDBM50605495 |
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| Synonyms: | CHEMBL5206215 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H16N2O4 |
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| Mol. Mass. | 324.3306 |
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| SMILES | CC(C)C(=O)Nc1ccc(cc1)-c1onc2ccc(cc12)C(O)=O |
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| Structure | 
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