| Reaction Details |
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 | Report a problem with these data |
| Target | Inositol hexakisphosphate kinase 2 |
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| Ligand | BDBM50605495 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2251835 (CHEMBL5166045) |
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| IC50 | 820±n/a nM |
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| Citation |  Zhou, Y; Mukherjee, S; Huang, D; Chakraborty, M; Gu, C; Zong, G; Stashko, MA; Pearce, KH; Shears, SB; Chakraborty, A; Wang, H; Wang, X Development of Novel IP6K Inhibitors for the Treatment of Obesity and Obesity-Induced Metabolic Dysfunctions. J Med Chem65:6869-6887 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Inositol hexakisphosphate kinase 2 |
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| Name: | Inositol hexakisphosphate kinase 2 |
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| Synonyms: | 2.7.4.- | IHPK2 | IP6K2 | IP6K2_HUMAN | Inositol hexakisphosphate kinase 2 | InsP6 kinase 2 | InsP6K2 | P(i)-uptake stimulator | PiUS |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49188.38 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_119238 |
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| Residue: | 426 |
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| Sequence: | MSPAFRAMDVEPRAKGVLLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYETLPAEMR
KFTPQYKGVVSVRFEEDEDRNLCLIAYPLKGDHGIVDIVDNSDCEPKSKLLRWTTNKKHH
VLETEKTPKDWVRQHRKEEKMKSHKLEEEFEWLKKSEVLYYTVEKKGNISSQLKHYNPWS
MKCHQQQLQRMKENAKHRNQYKFILLENLTSRYEVPCVLDLKMGTRQHGDDASEEKAANQ
IRKCQQSTSAVIGVRVCGMQVYQAGSGQLMFMNKYHGRKLSVQGFKEALFQFFHNGRYLR
RELLGPVLKKLTELKAVLERQESYRFYSSSLLVIYDGKERPEVVLDSDAEDLEDLSEESA
DESAGAYAYKPIGASSVDVRMIDFAHTTCRLYGEDTVVHEGQDAGYIFGLQSLIDIVTEI
SEESGE
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| BDBM50605495 |
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| n/a |
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| Name | BDBM50605495 |
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| Synonyms: | CHEMBL5206215 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H16N2O4 |
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| Mol. Mass. | 324.3306 |
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| SMILES | CC(C)C(=O)Nc1ccc(cc1)-c1onc2ccc(cc12)C(O)=O |
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| Structure | 
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