| Reaction Details |
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 | Report a problem with these data |
| Target | Target of rapamycin complex subunit LST8 |
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| Ligand | BDBM315573 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2261179 (CHEMBL5216190) |
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| IC50 | <5.0±n/a nM |
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| Citation |  Oleksak, P; Nepovimova, E; Chrienova, Z; Musilek, K; Patocka, J; Kuca, K Contemporary mTOR inhibitor scaffolds to diseases breakdown: A patent review (2015-2021). Eur J Med Chem238:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Target of rapamycin complex subunit LST8 |
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| Name: | Target of rapamycin complex subunit LST8 |
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| Synonyms: | G protein beta subunit-like | GBL | Gable | LST8 | LST8_HUMAN | MLST8 | Mammalian lethal with SEC13 protein 8 | Protein GbetaL | TORC subunit LST8 | Target of rapamycin complex subunit LST8 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35871.25 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_118692 |
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| Residue: | 326 |
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| Sequence: | MNTSPGTVGSDPVILATAGYDHTVRFWQAHSGICTRTVQHQDSQVNALEVTPDRSMIAAA
GYQHIRMYDLNSNNPNPIISYDGVNKNIASVGFHEDGRWMYTGGEDCTARIWDLRSRNLQ
CQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWDLKTDHNEQLIPEPEVSITSAHIDP
DASYMAAVNSTGNCYVWNLTGGIGDEVTQLIPKTKIPAHTRYALQCRFSPDSTLLATCSA
DQTCKIWRTSNFSLMTELSIKSGNPGESSRGWMWGCAFSGDSQYIVTASSDNLARLWCVE
TGEIKREYGGHQKAVVCLAFNDSVLG
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| BDBM315573 |
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| n/a |
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| Name | BDBM315573 |
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| Synonyms: | US10172858, Table 2.69 | US9828378, # 69 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20ClN7O2 |
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| Mol. Mass. | 425.871 |
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| SMILES | CC(=O)N1CCC(CC1)n1nc(-c2cc3c(Cl)ccc(O)c3[nH]2)c2c(N)ncnc12 |
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| Structure | 
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