| Reaction Details |
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 | Report a problem with these data |
| Target | REST corepressor 1 |
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| Ligand | BDBM50407721 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2267269 |
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| Ki | 28400±n/a nM |
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| Citation |  Dai, XJ; Liu, Y; Xue, LP; Xiong, XP; Zhou, Y; Zheng, YC; Liu, HM Reversible Lysine Specific Demethylase 1 (LSD1) Inhibitors: A Promising Wrench to Impair LSD1. J Med Chem64:2466-2488 (2021) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| REST corepressor 1 |
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| Name: | REST corepressor 1 |
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| Synonyms: | KIAA0071 | Protein CoREST | RCOR | RCOR1 | RCOR1_HUMAN | REST corepressor 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53329.34 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_108118 |
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| Residue: | 485 |
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| Sequence: | MPAMVEKGPEVSGKRRGRNNAAASASAAAASAAASAACASPAATAASGAAASSASAAAAS
AAAAPNNGQNKSLAAAAPNGNSSSNSWEEGSSGSSSDEEHGGGGMRVGPQYQAVVPDFDP
AKLARRSQERDNLGMLVWSPNQNLSEAKLDEYIAIAKEKHGYNMEQALGMLFWHKHNIEK
SLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTR
TKTSVMDRHARKQKREREESEDELEEANGNNPIDIEVDQNKESKKEVPPTETVPQVKKEK
HSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNS
ALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQV
KNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQKPVKSPDNSIKMPEEEDEAPVLDVR
YASAS
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| BDBM50407721 |
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| n/a |
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| Name | BDBM50407721 |
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| Synonyms: | CHEMBL5266466 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H55N9O8 |
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| Mol. Mass. | 717.856 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](C(C)C)C(O)=O |r| |
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| Structure | 
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