| Reaction Details |
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 | Report a problem with these data |
| Target | Transforming growth factor beta-1 proprotein |
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| Ligand | BDBM50610512 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2281209 |
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| IC50 | 56±n/a nM |
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| Citation |  Zhang, J; Zhang, Y; Qu, B; Yang, H; Hu, S; Dong, X If small molecules immunotherapy comes, can the prime be far behind? Eur J Med Chem218:0 (2021) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Transforming growth factor beta-1 proprotein |
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| Name: | Transforming growth factor beta-1 proprotein |
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| Synonyms: | LAP | Latency-associated peptide | TGF-beta-1 | TGFB | TGFB1 | Transforming growth factor beta-1 | Transforming growth factor beta-1 proprotein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44337.72 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_118308 |
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| Residue: | 390 |
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| Sequence: | MPPSGLRLLPLLLPLLWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
SPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVETHNEI
YDKFKQSTHSIYMFFNTSELREAVPEPVLLSRAELRLLRLKLKVEQHVELYQKYSNNSWR
YLSNRLLAPSDSPEWLSFDVTGVVRQWLSRGGEIEGFRLSAHCSCDSRDNTLQVDINGFT
TGRRGDLATIHGMNRPFLLLMATPLERAQHLQSSRHRRALDTNYCFSSTEKNCCVRQLYI
DFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQA
LEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
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| BDBM50610512 |
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| n/a |
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| Name | BDBM50610512 |
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| Synonyms: | CHEMBL5272606 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H19N5O |
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| Mol. Mass. | 369.4192 |
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| SMILES | Cc1cc(cc(n1)-c1cc2CCCn2n1)-c1ccnc2ccc(cc12)C(N)=O |
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| Structure | 
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