| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50198062 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_432539 (CHEMBL918833) |
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| Ki | 5.8±n/a nM |
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| Citation |  Collina, S; Loddo, G; Urbano, M; Linati, L; Callegari, A; Ortuso, F; Alcaro, S; Laggner, C; Langer, T; Prezzavento, O; Ronsisvalle, G; Azzolina, O Design, synthesis, and SAR analysis of novel selective sigma1 ligands. Bioorg Med Chem15:771-83 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50198062 |
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| n/a |
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| Name | BDBM50198062 |
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| Synonyms: | (R/S)-N-Benzyl-3-(biphenyl-4-yl)-N-methylbutan-1-amine | CHEMBL224151 | benzyl-(3-biphenyl-4-yl-butyl)-methyl-amine |
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| Type | Small organic molecule |
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| Emp. Form. | C24H27N |
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| Mol. Mass. | 329.4779 |
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| SMILES | CC(CCN(C)Cc1ccccc1)c1ccc(cc1)-c1ccccc1 |
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| Structure | 
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