| Reaction Details |
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 | Report a problem with these data |
| Target | Proteasome subunit beta type-5 |
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| Ligand | BDBM50199450 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_413589 (CHEMBL853870) |
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| IC50 | >10000±n/a nM |
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| Citation |  Adsule, S; Barve, V; Chen, D; Ahmed, F; Dou, QP; Padhye, S; Sarkar, FH Novel Schiff base copper complexes of quinoline-2 carboxaldehyde as proteasome inhibitors in human prostate cancer cells. J Med Chem49:7242-6 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Proteasome subunit beta type-5 |
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| Name: | Proteasome subunit beta type-5 |
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| Synonyms: | 20S proteasome chymotrypsin-like | 26S proteosome | LMPX | MB1 | PSB5_HUMAN | PSMB5 | Proteasome Macropain subunit MB1 | Proteasome subunit beta type-1/beta type-5 | X |
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| Type: | Protein |
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| Mol. Mass.: | 28480.96 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 263 |
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| Sequence: | MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGT
TTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLAR
QCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRI
SGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVRE
DGWIRVSSDNVADLHEKYSGSTP
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| BDBM50199450 |
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| n/a |
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| Name | BDBM50199450 |
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| Synonyms: | 1-(quinolin-2-ylmethylene)thiosemicarbazide | 2-(quinolin-2-ylmethylene)hydrazinecarbothioamide | CHEMBL215065 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H10N4S |
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| Mol. Mass. | 230.289 |
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| SMILES | NC(=S)NN=Cc1ccc2ccccc2n1 |w:5.5| |
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| Structure | 
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