| Reaction Details |
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 | Report a problem with these data |
| Target | Sodium channel subunit beta-2 |
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| Ligand | BDBM50613343 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2291913 |
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| IC50 | 1600±n/a nM |
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| Citation |  Karanjule, N; Hayashi, N; Suzuki, S; Tsuda, T; Tokumaru, E; Tanaka, K; Kimoto, H; Domon, Y; Takahashi, S; Kubota, K; Kitano, Y; Yokoyama, T; Koishi, R; Fujiwara, C; Inaba, S; Asano, D; Sakakura, T; Takasuna, K; Shinozuka, T -Aryl Indoles as a Novel Class of Potent Na ACS Med Chem Lett14:788-793 (2023) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sodium channel subunit beta-2 |
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| Name: | Sodium channel subunit beta-2 |
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| Synonyms: | Gm183 | SCN2B_MOUSE | Scn2b | Sodium channel subunit beta-2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 24227.48 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_119885 |
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| Residue: | 215 |
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| Sequence: | MHRDAWLPRPAFSLTGLSLFFSLVPPGRSMEVTAPTTLSVLNGSDTRLPCTFNSCYTVNH
KQFSLNWTYQECNNCTEEMFLQFRMKIINLKLERFGDRVEFSGNPSKYDVSVTLKNVQLE
DEGIYNCYITNPPDRHRGHGKIYLQVLLEVPPERDSTVAVIVGASVGGFLAVVILVLMVV
KCVRRKKEQKLSTDDLKTEEEGKMDGEGNAEDGTK
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| BDBM50613343 |
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| n/a |
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| Name | BDBM50613343 |
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| Synonyms: | CHEMBL5287784 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H16F3N3O3S |
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| Mol. Mass. | 423.409 |
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| SMILES | Cc1cn(-c2ccc(nc2)C(F)(F)F)c2ccc(cc12)C(=O)NS(=O)(=O)C1CC1 |
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| Structure | 
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