| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1A |
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| Ligand | BDBM50614142 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2295733 |
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| Ki | 5160±n/a nM |
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| Citation |  Asproni, B; Catto, M; Loriga, G; Murineddu, G; Corona, P; Purgatorio, R; Cichero, E; Fossa, P; Scarano, N; Martínez, AL; Brea, J; Pinna, GA Novel thienocycloalkylpyridazinones as useful scaffolds for acetylcholinesterase inhibition and serotonin 5-HT Bioorg Med Chem84:0 (2023) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1A |
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| Name: | 5-hydroxytryptamine receptor 1A |
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| Synonyms: | 5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A |
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| Type: | n/a |
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| Mol. Mass.: | 46122.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 422 |
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| Sequence: | MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
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| BDBM50614142 |
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| n/a |
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| Name | BDBM50614142 |
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| Synonyms: | CHEMBL5285645 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H39N5O3S2 |
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| Mol. Mass. | 629.835 |
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| SMILES | O=C1CC2Cc3ccsc3C2=NN1CCCCCCN1CCN(Cc2cccc3n(ccc23)S(=O)(=O)c2ccccc2)CC1 |c:12| |
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| Structure | 
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