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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cannabinoid receptor 1 | ||
| Ligand | BDBM50614204 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_2296049 | ||
| EC50 | 1875±n/a nM | ||
| Citation |  Dvorácskó, S; Dimmito, MP; Sebastiani, J; La Regina, G; Silvestri, R; Pieretti, S; Stefanucci, A; Tömböly, C; Mollica, A Rimonabant-Based Compounds Bearing Hydrophobic Amino Acid Derivatives as Cannabinoid Receptor Subtype 1 Ligands. ACS Med Chem Lett14:479-486 (2023) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cannabinoid receptor 1 | |||
| Name: | Cannabinoid receptor 1 | ||
| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 52856.55 | ||
| Organism: | Rattus norvegicus (rat) | ||
| Description: | P20272 | ||
| Residue: | 473 | ||
| Sequence: |
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| BDBM50614204 | |||
| n/a | |||
| Name | BDBM50614204 | ||
| Synonyms: | CHEMBL5280746 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H22Cl3N5O2 | ||
| Mol. Mass. | 482.791 | ||
| SMILES | Cc1c(nn(c1-n1cccc1Cl)-c1ccc(Cl)c(Cl)c1)C(=O)N[C@H](C(N)=O)C(C)(C)C |r,wU:23.29,(-2.33,3.09,;-1.46,1.83,;.08,1.8,;.52,.32,;-.75,-.56,;-1.97,.38,;-3.44,-.06,;-3.95,-1.51,;-5.49,-1.47,;-5.93,.01,;-4.66,.88,;-4.63,2.42,;-.78,-2.09,;-2.14,-2.82,;-2.18,-4.36,;-.86,-5.17,;-.9,-6.7,;.49,-4.42,;1.81,-5.22,;.53,-2.88,;1.01,3.02,;.42,4.44,;2.54,2.83,;3.47,4.05,;5,3.86,;5.93,5.08,;5.6,2.44,;2.87,5.48,;1.38,5.08,;1.78,6.57,;3.8,6.7,)| | ||
| Structure | 
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