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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Squalene synthase | ||
| Ligand | BDBM50270282 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_520603 (CHEMBL959525) | ||
| IC50 | >1000±n/a nM | ||
| Citation |  Cammerer, SB; Jimenez, C; Jones, S; Gros, L; Lorente, SO; Rodrigues, C; Rodrigues, JC; Caldera, A; Ruiz Perez, LM; da Souza, W; Kaiser, M; Brun, R; Urbina, JA; Gonzalez Pacanowska, D; Gilbert, IH Quinuclidine derivatives as potential antiparasitics. Antimicrob Agents Chemother51:4049-61 (2007) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Squalene synthase | |||
| Name: | Squalene synthase | ||
| Synonyms: | Farnesyltransferase, putative | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 47117.40 | ||
| Organism: | Leishmania major | ||
| Description: | ChEMBL_520603 | ||
| Residue: | 414 | ||
| Sequence: |
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| BDBM50270282 | |||
| n/a | |||
| Name | BDBM50270282 | ||
| Synonyms: | (E/Z)-3-benzylidenequinuclidine | CHEMBL478358 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C14H17N | ||
| Mol. Mass. | 199.2915 | ||
| SMILES | C1CN2CCC1\C(C2)=C\c1ccccc1 |(-9.93,3.02,;-9.93,1.47,;-8.6,.7,;-7.85,2.03,;-9.33,2.44,;-8.6,3.79,;-7.26,3.02,;-7.26,1.47,;-5.93,3.79,;-4.59,3.01,;-4.6,1.48,;-3.27,.71,;-1.94,1.47,;-1.94,3.02,;-3.27,3.78,)| | ||
| Structure | 
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