| Reaction Details |
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 | Report a problem with these data |
| Target | Acyl-CoA desaturase 1 |
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| Ligand | BDBM50262531 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_514601 (CHEMBL979979) |
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| IC50 | 700±n/a nM |
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| Citation |  Xin, Z; Zhao, H; Serby, MD; Liu, B; Liu, M; Szczepankiewicz, BG; Nelson, LT; Smith, HT; Suhar, TS; Janis, RS; Cao, N; Camp, HS; Collins, CA; Sham, HL; Surowy, TK; Liu, G Discovery of piperidine-aryl urea-based stearoyl-CoA desaturase 1 inhibitors. Bioorg Med Chem Lett18:4298-302 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Acyl-CoA desaturase 1 |
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| Name: | Acyl-CoA desaturase 1 |
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| Synonyms: | ACOD1_MOUSE | Scd1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41064.54 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1462109 |
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| Residue: | 355 |
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| Sequence: | MPAHMLQEISSSYTTTTTITAPPSGNEREKVKTVPLHLEEDIRPEMKEDIHDPTYQDEEG
PPPKLEYVWRNIILMVLLHLGGLYGIILVPSCKLYTCLFGIFYYMTSALGITAGAHRLWS
HRTYKARLPLRIFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGW
LLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGLLLMCFILPTLVPWYCWGETFVN
SLFVSTFLRYTLVLNATWLVNSAAHLYGYRPYDKNIQSRENILVSLGAVGEGFHNYHHTF
PFDYSASEYRWHINFTTFFIDCMAALGLAYDRKKVSKATVLARIKRTGDGSHKSS
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| BDBM50262531 |
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| n/a |
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| Name | BDBM50262531 |
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| Synonyms: | CHEMBL476103 | N-(3-(methylcarbamoyl)phenyl)-4-(2-(trifluoromethyl)benzoyl)piperazine-1-carboxamide |
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| Type | Small organic molecule |
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| Emp. Form. | C21H21F3N4O3 |
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| Mol. Mass. | 434.4116 |
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| SMILES | CNC(=O)c1cccc(NC(=O)N2CCN(CC2)C(=O)c2ccccc2C(F)(F)F)c1 |
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| Structure | 
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