Reaction Details | |||
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Target | 5-hydroxytryptamine receptor 1A | ||
Ligand | BDBM50262513 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_509628 (CHEMBL1003956) | ||
Ki | 5670±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
5-hydroxytryptamine receptor 1A | |||
Name: | 5-hydroxytryptamine receptor 1A | ||
Synonyms: | 5-HT-1A | 5-HT1 | 5-HT1A | 5-Hydroxytryptamine receptor 1A (5-HT1A) | 5-hydroxytryptamine receptor 1A (5HT1A) | 5HT1A_RAT | 5ht1a | G-21 | Htr1a | Serotonin 1 (5-HT1) receptor | Serotonin 1a (5-HT1a) receptor/Adrenergic receptor alpha-1 | Serotonin receptor 1A | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 46445.29 | ||
Organism: | Rattus norvegicus (rat) | ||
Description: | Binding assays were performed using rat hippocampal membranes. | ||
Residue: | 422 | ||
Sequence: |
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BDBM50262513 | |||
n/a | |||
Name | BDBM50262513 | ||
Synonyms: | CHEMBL449277 | cis-3-(4-(6-(3-fluoropropoxy)-3,4-dihydroisoquinolin-2(1H)-yl)cyclohexyl)-1H-indole-5-carbonitrile | ||
Type | Small organic molecule | ||
Emp. Form. | C27H30FN3O | ||
Mol. Mass. | 431.545 | ||
SMILES | FCCCOc1ccc2CN(CCc2c1)[C@H]1CC[C@H](CC1)c1c[nH]c2ccc(cc12)C#N |r,wU:15.16,18.23,(10.45,-15.31,;10.45,-13.77,;9.11,-13,;9.12,-11.46,;7.78,-10.69,;6.45,-11.46,;6.45,-13,;5.11,-13.76,;3.79,-12.99,;2.46,-13.76,;1.13,-12.98,;1.13,-11.45,;2.47,-10.68,;3.8,-11.45,;5.13,-10.69,;-.2,-13.75,;-.2,-15.29,;-1.53,-16.06,;-2.87,-15.28,;-2.88,-13.76,;-1.54,-12.98,;-4.2,-16.06,;-4.35,-17.6,;-5.87,-17.93,;-6.65,-16.59,;-8.16,-16.28,;-8.64,-14.82,;-7.61,-13.66,;-6.11,-13.97,;-5.62,-15.43,;-8.09,-12.2,;-8.58,-10.74,)| | ||
Structure | ![]() |