| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Kinesin-like protein KIF11 |
|---|
| Ligand | BDBM50276406 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_540860 (CHEMBL1023928) |
|---|
| IC50 | 40±n/a nM |
|---|
| Citation |  Matsuno, K; Sawada, J; Sugimoto, M; Ogo, N; Asai, A Bis(hetero)aryl derivatives as unique kinesin spindle protein inhibitors. Bioorg Med Chem Lett19:1058-61 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Kinesin-like protein KIF11 |
|---|
| Name: | Kinesin-like protein KIF11 |
|---|
| Synonyms: | EG5 | KIF11 | KIF11_HUMAN | KNSL1 | Kinesin Spindle Protein Eg5 | Kinesin-like protein 1 | TRIP5 | kinesin spindle protein |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 119138.97 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1457426 |
|---|
| Residue: | 1056 |
|---|
| Sequence: | MASQPNSSAKKKEEKGKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADK
SSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERS
PNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSE
RLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFS
VTIHMKETTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVIT
ALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNIL
NKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENFRVMSGKLTVQEEQIV
ELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEY
ITSALESTEEKLHDAASKLLNTVEETTKDVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNS
LFNNMEELIKDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTHV
SQIFNMILKEQSLAAESKTVLQELINVLKTDLLSSLEMILSPTVVSILKINSQLKHIFKT
SLTVADKIEDQKKELDGFLSILCNNLHELQENTICSLVESQKQCGNLTEDLKTIKQTHSQ
ELCKLMNLWTERFCALEEKCENIQKPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFS
QELRNFNQEGTKLVEESVKHSDKLNGNLEKISQETEQRCESLNTRTVYFSEQWVSSLNER
EQELHNLLEVVSQCCEASSSDITEKSDGRKAAHEKQHNIFLDQMTIDEDKLIAQNLELNE
TIKIGLTKLNCFLEQDLKLDIPTGTTPQRKSYLYPSTLVRTEPREHLLDQLKRKQPELLM
MLNCSENNKEETIPDVDVEEAVLGQYTEEPLSQEPSVDAGVDCSSIGGVPFFQHKKSHGK
DKENRGINTLERSKVEETTEHLVTKSRLPLRAQINL
|
|
|
|---|
| BDBM50276406 |
|---|
| n/a |
|---|
| Name | BDBM50276406 |
|---|
| Synonyms: | CHEMBL470767 | N-{5-[3-fluoro-4-(trifluoromethyl)phenyl]pyridin-2-yl}sulfamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H9F4N3O2S |
|---|
| Mol. Mass. | 335.277 |
|---|
| SMILES | NS(=O)(=O)Nc1ccc(cn1)-c1ccc(c(F)c1)C(F)(F)F |
|---|
| Structure | 
|
|---|
Search and Browse
