Compile Data Set for Download or QSAR

Found 183 hits with Last Name = 'sawada' and Initial = 'j'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50131845 (CHEMBL3633535) Show SMILES COc1ccc(cc1)C1(SC[C@H](N)C(O)=O)c2ccccc2C=Cc2ccccc12 |r,c:24| Show InChI InChI=1S/C25H23NO3S/c1-29-20-14-12-19(13-15-20)25(30-16-23(26)24(27)28)21-8-4-2-6-17(21)10-11-18-7-3-5-9-22(18)25/h2-15,23H,16,26H2,1H3,(H,27,28)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Binding affinity against delta opioid receptor in mouse hot plate test				ACS Med Chem Lett 6: 1004-9 (2015) Article DOI: 10.1021/acsmedchemlett.5b00221 BindingDB Entry DOI: 10.7270/Q2WM1G76
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50131854 (CHEMBL3633526) Show SMILES Cc1ccc(cc1)C1(SC[C@H](N)C(O)=O)c2ccccc2CCc2ccccc12 |r| Show InChI InChI=1S/C25H25NO2S/c1-17-10-14-20(15-11-17)25(29-16-23(26)24(27)28)21-8-4-2-6-18(21)12-13-19-7-3-5-9-22(19)25/h2-11,14-15,23H,12-13,16,26H2,1H3,(H,27,28)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Binding affinity against delta opioid receptor in mouse hot plate test				ACS Med Chem Lett 6: 1004-9 (2015) Article DOI: 10.1021/acsmedchemlett.5b00221 BindingDB Entry DOI: 10.7270/Q2WM1G76
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50131853 (CHEMBL3633527) Show SMILES N[C@@H](CSC1(c2ccc(Cl)cc2)c2ccccc2CCc2ccccc12)C(O)=O |r| Show InChI InChI=1S/C24H22ClNO2S/c25-19-13-11-18(12-14-19)24(29-15-22(26)23(27)28)20-7-3-1-5-16(20)9-10-17-6-2-4-8-21(17)24/h1-8,11-14,22H,9-10,15,26H2,(H,27,28)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Binding affinity against delta opioid receptor in mouse hot plate test				ACS Med Chem Lett 6: 1004-9 (2015) Article DOI: 10.1021/acsmedchemlett.5b00221 BindingDB Entry DOI: 10.7270/Q2WM1G76
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50131859 (CHEMBL3633537) Show SMILES N[C@@H](CSC1(c2ccc(Cl)cc2)c2ccccc2C=Cc2ccccc12)C(O)=O |r,c:20| Show InChI InChI=1S/C24H20ClNO2S/c25-19-13-11-18(12-14-19)24(29-15-22(26)23(27)28)20-7-3-1-5-16(20)9-10-17-6-2-4-8-21(17)24/h1-14,22H,15,26H2,(H,27,28)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Binding affinity against delta opioid receptor in mouse hot plate test				ACS Med Chem Lett 6: 1004-9 (2015) Article DOI: 10.1021/acsmedchemlett.5b00221 BindingDB Entry DOI: 10.7270/Q2WM1G76
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50131855 (CHEMBL3633366) Show SMILES COc1ccc(cc1)C1(SC[C@H](N)C(O)=O)c2ccccc2CCc2ccccc12 |r| Show InChI InChI=1S/C25H25NO3S/c1-29-20-14-12-19(13-15-20)25(30-16-23(26)24(27)28)21-8-4-2-6-17(21)10-11-18-7-3-5-9-22(18)25/h2-9,12-15,23H,10-11,16,26H2,1H3,(H,27,28)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Binding affinity against delta opioid receptor in mouse hot plate test				ACS Med Chem Lett 6: 1004-9 (2015) Article DOI: 10.1021/acsmedchemlett.5b00221 BindingDB Entry DOI: 10.7270/Q2WM1G76
					More data for this Ligand-Target Pair				3D Structure (crystal)
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50131858 (CHEMBL3633536) Show SMILES Cc1ccc(cc1)C1(SC[C@H](N)C(O)=O)c2ccccc2C=Cc2ccccc12 |r,c:23| Show InChI InChI=1S/C25H23NO2S/c1-17-10-14-20(15-11-17)25(29-16-23(26)24(27)28)21-8-4-2-6-18(21)12-13-19-7-3-5-9-22(19)25/h2-15,23H,16,26H2,1H3,(H,27,28)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Binding affinity against delta opioid receptor in mouse hot plate test				ACS Med Chem Lett 6: 1004-9 (2015) Article DOI: 10.1021/acsmedchemlett.5b00221 BindingDB Entry DOI: 10.7270/Q2WM1G76
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50431893 (ARRY-520 | CHEMBL2347655) Show SMILES CON(C)C(=O)N1N=C(S[C@@]1(CCCN)c1ccccc1)c1cc(F)ccc1F |r,c:7| Show InChI InChI=1S/C20H22F2N4O2S/c1-25(28-2)19(27)26-20(11-6-12-23,14-7-4-3-5-8-14)29-18(24-26)16-13-15(21)9-10-17(16)22/h3-5,7-10,13H,6,11-12,23H2,1-2H3/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Binding affinity against delta opioid receptor in mouse hot plate test				ACS Med Chem Lett 6: 1004-9 (2015) Article DOI: 10.1021/acsmedchemlett.5b00221 BindingDB Entry DOI: 10.7270/Q2WM1G76
					More data for this Ligand-Target Pair				3D Structure (crystal)
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50220159 (CHEMBL389589 | N-[3'-fluoro-4'-(trifluoromethyl)-1...) Show SMILES NS(=O)(=O)Nc1ccc(cc1)-c1ccc(c(F)c1)C(F)(F)F Show InChI InChI=1S/C13H10F4N2O2S/c14-12-7-9(3-6-11(12)13(15,16)17)8-1-4-10(5-2-8)19-22(18,20)21/h1-7,19H,(H2,18,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Inhibition of microtubule-stimulated recombinant Eg5 (unknown origin) assessed as inhibition ATP hydrolysis by luminescent kinase assay				Bioorg Med Chem Lett 19: 1058-61 (2009) Article DOI: 10.1016/j.bmcl.2009.01.018 BindingDB Entry DOI: 10.7270/Q20R9P8G
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50131856 (CHEMBL3633365) Show SMILES N[C@@H](CSC1(c2ccc(cc2)C(F)(F)F)c2ccccc2CCc2ccccc12)C(O)=O |r| Show InChI InChI=1S/C25H22F3NO2S/c26-25(27,28)19-13-11-18(12-14-19)24(32-15-22(29)23(30)31)20-7-3-1-5-16(20)9-10-17-6-2-4-8-21(17)24/h1-8,11-14,22H,9-10,15,29H2,(H,30,31)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Binding affinity against delta opioid receptor in mouse hot plate test				ACS Med Chem Lett 6: 1004-9 (2015) Article DOI: 10.1021/acsmedchemlett.5b00221 BindingDB Entry DOI: 10.7270/Q2WM1G76
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50131856 (CHEMBL3633365) Show SMILES N[C@@H](CSC1(c2ccc(cc2)C(F)(F)F)c2ccccc2CCc2ccccc12)C(O)=O |r| Show InChI InChI=1S/C25H22F3NO2S/c26-25(27,28)19-13-11-18(12-14-19)24(32-15-22(29)23(30)31)20-7-3-1-5-16(20)9-10-17-6-2-4-8-21(17)24/h1-8,11-14,22H,9-10,15,29H2,(H,30,31)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition C-terminal His-tagged KSP motor domain(1 to 369 residues) (unknown origin) expressed in bacteria assessed as inhibition of microtubule-sti...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113288 BindingDB Entry DOI: 10.7270/Q2668HXW
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50347610 (CHEMBL1802990) Show SMILES FC(F)(F)c1ccc2c(c1)[nH]c1cc3NC(=O)CCc3cc21 Show InChI InChI=1S/C16H11F3N2O/c17-16(18,19)9-2-3-10-11-5-8-1-4-15(22)21-12(8)7-14(11)20-13(10)6-9/h2-3,5-7,20H,1,4H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assay				J Med Chem 54: 4839-46 (2011) Article DOI: 10.1021/jm200448n BindingDB Entry DOI: 10.7270/Q20V8D5G
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50017887 (CHEMBL3289009) Show SMILES FC(F)(F)c1ccnc(Nc2ccc3NC(=O)CSc3c2)c1 Show InChI InChI=1S/C14H10F3N3OS/c15-14(16,17)8-3-4-18-12(5-8)19-9-1-2-10-11(6-9)22-7-13(21)20-10/h1-6H,7H2,(H,18,19)(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminal His-tagged KSP ATPase motor domain (unknown origin) expressed in bacteria incubated for 30 mins prior to ATP addition measur...				Bioorg Med Chem 22: 3171-9 (2014) Article DOI: 10.1016/j.bmc.2014.04.008 BindingDB Entry DOI: 10.7270/Q2ST7RD5
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50131846 (CHEMBL3633534) Show SMILES N[C@@H](CSC1(c2ccc(cc2)C(F)(F)F)c2ccccc2C=Cc2ccccc12)C(O)=O |r,c:23| Show InChI InChI=1S/C25H20F3NO2S/c26-25(27,28)19-13-11-18(12-14-19)24(32-15-22(29)23(30)31)20-7-3-1-5-16(20)9-10-17-6-2-4-8-21(17)24/h1-14,22H,15,29H2,(H,30,31)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Binding affinity against delta opioid receptor in mouse hot plate test				ACS Med Chem Lett 6: 1004-9 (2015) Article DOI: 10.1021/acsmedchemlett.5b00221 BindingDB Entry DOI: 10.7270/Q2WM1G76
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50347615 (CHEMBL1803019) Show SMILES FC(F)(F)c1ccc2c(c1)[nH]c1cc3NC(=O)Cc3cc21 Show InChI InChI=1S/C15H9F3N2O/c16-15(17,18)8-1-2-9-10-3-7-4-14(21)20-11(7)6-13(10)19-12(9)5-8/h1-3,5-6,19H,4H2,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assay				J Med Chem 54: 4839-46 (2011) Article DOI: 10.1021/jm200448n BindingDB Entry DOI: 10.7270/Q20V8D5G
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50276406 (CHEMBL470767 | N-{5-[3-fluoro-4-(trifluoromethyl)p...) Show SMILES NS(=O)(=O)Nc1ccc(cn1)-c1ccc(c(F)c1)C(F)(F)F Show InChI InChI=1S/C12H9F4N3O2S/c13-10-5-7(1-3-9(10)12(14,15)16)8-2-4-11(18-6-8)19-22(17,20)21/h1-6H,(H,18,19)(H2,17,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Inhibition of microtubule-stimulated recombinant Eg5 (unknown origin) assessed as inhibition ATP hydrolysis by luminescent kinase assay				Bioorg Med Chem Lett 19: 1058-61 (2009) Article DOI: 10.1016/j.bmcl.2009.01.018 BindingDB Entry DOI: 10.7270/Q20R9P8G
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50347609 (CHEMBL1802989) Show SMILES FC(F)(F)c1ccc2c(c1)[nH]c1c3CCC(=O)Nc3ccc21 Show InChI InChI=1S/C16H11F3N2O/c17-16(18,19)8-1-2-9-10-3-5-12-11(4-6-14(22)20-12)15(10)21-13(9)7-8/h1-3,5,7,21H,4,6H2,(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assay				J Med Chem 54: 4839-46 (2011) Article DOI: 10.1021/jm200448n BindingDB Entry DOI: 10.7270/Q20V8D5G
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50563618 (CHEMBL4754888) Show SMILES NCCOCCOCCNC(=O)C(N)CSC1(c2ccc(cc2)C(F)(F)F)c2ccccc2CCc2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition C-terminal His-tagged KSP motor domain(1 to 369 residues) (unknown origin) expressed in bacteria assessed as inhibition of microtubule-sti...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113288 BindingDB Entry DOI: 10.7270/Q2668HXW
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50017707 (CHEMBL3288965) Show SMILES [O-][N+](=O)c1ccc2[nH]c3cc(ccc3c2c1)C(F)(F)F Show InChI InChI=1S/C13H7F3N2O2/c14-13(15,16)7-1-3-9-10-6-8(18(19)20)2-4-11(10)17-12(9)5-7/h1-6,17H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminal His-tagged KSP ATPase motor domain (unknown origin) expressed in bacteria incubated for 30 mins prior to ATP addition measur...				Bioorg Med Chem 22: 3171-9 (2014) Article DOI: 10.1016/j.bmc.2014.04.008 BindingDB Entry DOI: 10.7270/Q2ST7RD5
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50347616 (CHEMBL1803020) Show SMILES FC(F)(F)c1ccc2c(c1)[nH]c1cc3NC(=O)CCCc3cc21 Show InChI InChI=1S/C17H13F3N2O/c18-17(19,20)10-4-5-11-12-6-9-2-1-3-16(23)22-13(9)8-15(12)21-14(11)7-10/h4-8,21H,1-3H2,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assay				J Med Chem 54: 4839-46 (2011) Article DOI: 10.1021/jm200448n BindingDB Entry DOI: 10.7270/Q20V8D5G
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50017722 (CHEMBL3288973) Show SMILES FC(F)(F)c1cccc(Nc2ccc3NC(=O)CCc3c2)c1 Show InChI InChI=1S/C16H13F3N2O/c17-16(18,19)11-2-1-3-12(9-11)20-13-5-6-14-10(8-13)4-7-15(22)21-14/h1-3,5-6,8-9,20H,4,7H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminal His-tagged KSP ATPase motor domain (unknown origin) expressed in bacteria incubated for 30 mins prior to ATP addition measur...				Bioorg Med Chem 22: 3171-9 (2014) Article DOI: 10.1016/j.bmc.2014.04.008 BindingDB Entry DOI: 10.7270/Q2ST7RD5
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM36350 (6-[4-(Trifluoromethyl)phenyl]-3,4-dihydro-2(1H)-qu...) Show SMILES FC(F)(F)c1ccc(cc1)-c1ccc2NC(=O)CCc2c1 Show InChI InChI=1S/C16H12F3NO/c17-16(18,19)13-5-1-10(2-6-13)11-3-7-14-12(9-11)4-8-15(21)20-14/h1-3,5-7,9H,4,8H2,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assay				J Med Chem 54: 4839-46 (2011) Article DOI: 10.1021/jm200448n BindingDB Entry DOI: 10.7270/Q20V8D5G
					More data for this Ligand-Target Pair				3D Structure (crystal)
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50382559 (ISPINESIB) Show SMILES CC(C)[C@@H](N(CCCN)C(=O)c1ccc(C)cc1)c1nc2cc(Cl)ccc2c(=O)n1Cc1ccccc1 Show InChI InChI=1S/C30H33ClN4O2/c1-20(2)27(34(17-7-16-32)29(36)23-12-10-21(3)11-13-23)28-33-26-18-24(31)14-15-25(26)30(37)35(28)19-22-8-5-4-6-9-22/h4-6,8-15,18,20,27H,7,16-17,19,32H2,1-3H3/t27-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Binding affinity against delta opioid receptor in mouse hot plate test				ACS Med Chem Lett 6: 1004-9 (2015) Article DOI: 10.1021/acsmedchemlett.5b00221 BindingDB Entry DOI: 10.7270/Q2WM1G76
					More data for this Ligand-Target Pair				3D Structure (crystal)
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50017888 (CHEMBL3289010) Show SMILES FC(F)(F)c1ccnc(Nc2ccc3NC(=O)CCCc3c2)c1 Show InChI InChI=1S/C16H14F3N3O/c17-16(18,19)11-6-7-20-14(9-11)21-12-4-5-13-10(8-12)2-1-3-15(23)22-13/h4-9H,1-3H2,(H,20,21)(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminal His-tagged KSP ATPase motor domain (unknown origin) expressed in bacteria incubated for 30 mins prior to ATP addition measur...				Bioorg Med Chem 22: 3171-9 (2014) Article DOI: 10.1016/j.bmc.2014.04.008 BindingDB Entry DOI: 10.7270/Q2ST7RD5
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50017884 (CHEMBL3289006) Show SMILES FC(F)(F)c1cccc(Nc2ccc3NC(=O)CCCc3c2)c1 Show InChI InChI=1S/C17H15F3N2O/c18-17(19,20)12-4-2-5-13(10-12)21-14-7-8-15-11(9-14)3-1-6-16(23)22-15/h2,4-5,7-10,21H,1,3,6H2,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminal His-tagged KSP ATPase motor domain (unknown origin) expressed in bacteria incubated for 30 mins prior to ATP addition measur...				Bioorg Med Chem 22: 3171-9 (2014) Article DOI: 10.1016/j.bmc.2014.04.008 BindingDB Entry DOI: 10.7270/Q2ST7RD5
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50017881 (CHEMBL3289003) Show SMILES FC(F)(F)c1cccc(Nc2ccc3NC(=O)CSc3c2)c1 Show InChI InChI=1S/C15H11F3N2OS/c16-15(17,18)9-2-1-3-10(6-9)19-11-4-5-12-13(7-11)22-8-14(21)20-12/h1-7,19H,8H2,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminal His-tagged KSP ATPase motor domain (unknown origin) expressed in bacteria incubated for 30 mins prior to ATP addition measur...				Bioorg Med Chem 22: 3171-9 (2014) Article DOI: 10.1016/j.bmc.2014.04.008 BindingDB Entry DOI: 10.7270/Q2ST7RD5
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50347606 (CHEMBL1802986) Show SMILES FC(F)(F)c1ccc2c(c1)[nH]c1cnccc21 Show InChI InChI=1S/C12H7F3N2/c13-12(14,15)7-1-2-8-9-3-4-16-6-11(9)17-10(8)5-7/h1-6,17H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assay				J Med Chem 54: 4839-46 (2011) Article DOI: 10.1021/jm200448n BindingDB Entry DOI: 10.7270/Q20V8D5G
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50347606 (CHEMBL1802986) Show SMILES FC(F)(F)c1ccc2c(c1)[nH]c1cnccc21 Show InChI InChI=1S/C12H7F3N2/c13-12(14,15)7-1-2-8-9-3-4-16-6-11(9)17-10(8)5-7/h1-6,17H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminal His-tagged KSP ATPase motor domain (unknown origin) expressed in bacteria incubated for 30 mins prior to ATP addition measur...				Bioorg Med Chem 22: 3171-9 (2014) Article DOI: 10.1016/j.bmc.2014.04.008 BindingDB Entry DOI: 10.7270/Q2ST7RD5
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50563616 (CHEMBL4755438) Show SMILES CN(C)CCNC(=O)C(N)CSC1(c2ccc(cc2)C(F)(F)F)c2ccccc2CCc2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition C-terminal His-tagged KSP motor domain(1 to 369 residues) (unknown origin) expressed in bacteria assessed as inhibition of microtubule-sti...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113288 BindingDB Entry DOI: 10.7270/Q2668HXW
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50347617 (CHEMBL1803021) Show SMILES FC(F)(F)c1ccc2c(c1)[nH]c1c3CCCC(=O)Nc3ccc21 Show InChI InChI=1S/C17H13F3N2O/c18-17(19,20)9-4-5-10-11-6-7-13-12(2-1-3-15(23)21-13)16(11)22-14(10)8-9/h4-8,22H,1-3H2,(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assay				J Med Chem 54: 4839-46 (2011) Article DOI: 10.1021/jm200448n BindingDB Entry DOI: 10.7270/Q20V8D5G
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50131893 (CHEMBL3633541) Show SMILES N[C@@H](CSC1(c2ccc(cc2)C(F)(F)F)c2ccccc2CSc2ccccc12)C(O)=O |r| Show InChI InChI=1S/C24H20F3NO2S2/c25-24(26,27)17-11-9-16(10-12-17)23(32-14-20(28)22(29)30)18-6-2-1-5-15(18)13-31-21-8-4-3-7-19(21)23/h1-12,20H,13-14,28H2,(H,29,30)/t20-,23?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Binding affinity against delta opioid receptor in mouse hot plate test				ACS Med Chem Lett 6: 1004-9 (2015) Article DOI: 10.1021/acsmedchemlett.5b00221 BindingDB Entry DOI: 10.7270/Q2WM1G76
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50017838 (CHEMBL3288994) Show SMILES FC(F)(F)c1ccnc(Nc2ccc3NC(=O)CCc3c2)c1 Show InChI InChI=1S/C15H12F3N3O/c16-15(17,18)10-5-6-19-13(8-10)20-11-2-3-12-9(7-11)1-4-14(22)21-12/h2-3,5-8H,1,4H2,(H,19,20)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminal His-tagged KSP ATPase motor domain (unknown origin) expressed in bacteria incubated for 30 mins prior to ATP addition measur...				Bioorg Med Chem 22: 3171-9 (2014) Article DOI: 10.1016/j.bmc.2014.04.008 BindingDB Entry DOI: 10.7270/Q2ST7RD5
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50131879 (CHEMBL3633540) Show SMILES N[C@@H](CSC1(c2ccc(cc2)C(F)(F)F)c2ccccc2COc2ccccc12)C(O)=O |r| Show InChI InChI=1S/C24H20F3NO3S/c25-24(26,27)17-11-9-16(10-12-17)23(32-14-20(28)22(29)30)18-6-2-1-5-15(18)13-31-21-8-4-3-7-19(21)23/h1-12,20H,13-14,28H2,(H,29,30)/t20-,23?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Binding affinity against delta opioid receptor in mouse hot plate test				ACS Med Chem Lett 6: 1004-9 (2015) Article DOI: 10.1021/acsmedchemlett.5b00221 BindingDB Entry DOI: 10.7270/Q2WM1G76
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50563615 (CHEMBL4791487) Show SMILES NC(CSC1(c2ccc(cc2)C(F)(F)F)c2ccccc2CCc2ccccc12)C(=O)NCCO Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition C-terminal His-tagged KSP motor domain(1 to 369 residues) (unknown origin) expressed in bacteria assessed as inhibition of microtubule-sti...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113288 BindingDB Entry DOI: 10.7270/Q2668HXW
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50347612 (CHEMBL1803016) Show SMILES FC(F)(F)c1ccc2c(c1)[nH]c1ccc3NC(=O)CCc3c21 Show InChI InChI=1S/C16H11F3N2O/c17-16(18,19)8-1-2-10-13(7-8)20-12-5-4-11-9(15(10)12)3-6-14(22)21-11/h1-2,4-5,7,20H,3,6H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assay				J Med Chem 54: 4839-46 (2011) Article DOI: 10.1021/jm200448n BindingDB Entry DOI: 10.7270/Q20V8D5G
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50347613 (CHEMBL1803017) Show SMILES NC(=O)Nc1ccc2c(c1)[nH]c1cc(ccc21)C(F)(F)F Show InChI InChI=1S/C14H10F3N3O/c15-14(16,17)7-1-3-9-10-4-2-8(19-13(18)21)6-12(10)20-11(9)5-7/h1-6,20H,(H3,18,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assay				J Med Chem 54: 4839-46 (2011) Article DOI: 10.1021/jm200448n BindingDB Entry DOI: 10.7270/Q20V8D5G
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50017706 (CHEMBL3288964) Show SMILES CC(=O)Nc1ccc2c(c1)[nH]c1cc(ccc21)C(F)(F)F Show InChI InChI=1S/C15H11F3N2O/c1-8(21)19-10-3-5-12-11-4-2-9(15(16,17)18)6-13(11)20-14(12)7-10/h2-7,20H,1H3,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminal His-tagged KSP ATPase motor domain (unknown origin) expressed in bacteria incubated for 30 mins prior to ATP addition measur...				Bioorg Med Chem 22: 3171-9 (2014) Article DOI: 10.1016/j.bmc.2014.04.008 BindingDB Entry DOI: 10.7270/Q2ST7RD5
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50347607 (CHEMBL1802987) Show SMILES FC(F)(F)c1ccc2c(c1)[nH]c1ccncc21 Show InChI InChI=1S/C12H7F3N2/c13-12(14,15)7-1-2-8-9-6-16-4-3-10(9)17-11(8)5-7/h1-6,17H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assay				J Med Chem 54: 4839-46 (2011) Article DOI: 10.1021/jm200448n BindingDB Entry DOI: 10.7270/Q20V8D5G
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50347607 (CHEMBL1802987) Show SMILES FC(F)(F)c1ccc2c(c1)[nH]c1ccncc21 Show InChI InChI=1S/C12H7F3N2/c13-12(14,15)7-1-2-8-9-6-16-4-3-10(9)17-11(8)5-7/h1-6,17H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminal His-tagged KSP ATPase motor domain (unknown origin) expressed in bacteria incubated for 30 mins prior to ATP addition measur...				Bioorg Med Chem 22: 3171-9 (2014) Article DOI: 10.1016/j.bmc.2014.04.008 BindingDB Entry DOI: 10.7270/Q2ST7RD5
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50220185 (1-(3-fluoro-4'-(trifluoromethyl)biphenyl-4-yl)urea...) Show SMILES NC(=O)Nc1ccc(cc1F)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C14H10F4N2O/c15-11-7-9(3-6-12(11)20-13(19)21)8-1-4-10(5-2-8)14(16,17)18/h1-7H,(H3,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assay				J Med Chem 54: 4839-46 (2011) Article DOI: 10.1021/jm200448n BindingDB Entry DOI: 10.7270/Q20V8D5G
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50347614 (CHEMBL1803018) Show SMILES NC(=O)Nc1ccc2[nH]c3cc(ccc3c2c1)C(F)(F)F Show InChI InChI=1S/C14H10F3N3O/c15-14(16,17)7-1-3-9-10-6-8(19-13(18)21)2-4-11(10)20-12(9)5-7/h1-6,20H,(H3,18,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminal His-tagged KSP ATPase motor domain (unknown origin) expressed in bacteria incubated for 30 mins prior to ATP addition measur...				Bioorg Med Chem 22: 3171-9 (2014) Article DOI: 10.1016/j.bmc.2014.04.008 BindingDB Entry DOI: 10.7270/Q2ST7RD5
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50276289 (3'-fluoro-4'-(trifluoromethyl)biphenyl-4-sulfonami...) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1ccc(c(F)c1)C(F)(F)F Show InChI InChI=1S/C13H9F4NO2S/c14-12-7-9(3-6-11(12)13(15,16)17)8-1-4-10(5-2-8)21(18,19)20/h1-7H,(H2,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Inhibition of microtubule-stimulated recombinant Eg5 (unknown origin) assessed as inhibition ATP hydrolysis by luminescent kinase assay				Bioorg Med Chem Lett 19: 1058-61 (2009) Article DOI: 10.1016/j.bmcl.2009.01.018 BindingDB Entry DOI: 10.7270/Q20R9P8G
					More data for this Ligand-Target Pair				3D Structure (crystal)
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50347614 (CHEMBL1803018) Show SMILES NC(=O)Nc1ccc2[nH]c3cc(ccc3c2c1)C(F)(F)F Show InChI InChI=1S/C14H10F3N3O/c15-14(16,17)7-1-3-9-10-6-8(19-13(18)21)2-4-11(10)20-12(9)5-7/h1-6,20H,(H3,18,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assay				J Med Chem 54: 4839-46 (2011) Article DOI: 10.1021/jm200448n BindingDB Entry DOI: 10.7270/Q20V8D5G
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50220162 (CHEMBL243883 | N-[4'-(trifluoromethyl)-4-biphenyly...) Show SMILES NC(=O)Nc1ccc(cc1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C14H11F3N2O/c15-14(16,17)11-5-1-9(2-6-11)10-3-7-12(8-4-10)19-13(18)20/h1-8H,(H3,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assay				J Med Chem 54: 4839-46 (2011) Article DOI: 10.1021/jm200448n BindingDB Entry DOI: 10.7270/Q20V8D5G
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50563617 (CHEMBL4758507) Show SMILES NC(CSC1(c2ccc(cc2)C(F)(F)F)c2ccccc2CCc2ccccc12)C(=O)NCCN1CCCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	146	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition C-terminal His-tagged KSP motor domain(1 to 369 residues) (unknown origin) expressed in bacteria assessed as inhibition of microtubule-sti...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113288 BindingDB Entry DOI: 10.7270/Q2668HXW
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM23823 ((2R)-2-amino-3-{[(4-methoxyphenyl)diphenylmethyl]s...) Show SMILES COc1ccc(cc1)C(SC[C@H](N)C(O)=O)(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C23H23NO3S/c1-27-20-14-12-19(13-15-20)23(17-8-4-2-5-9-17,18-10-6-3-7-11-18)28-16-21(24)22(25)26/h2-15,21H,16,24H2,1H3,(H,25,26)/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Inhibition of Eg5 assessed as inhibition ATP hydrolysis by ATPase assay				Bioorg Med Chem Lett 17: 3921-4 (2007) Article DOI: 10.1016/j.bmcl.2007.04.101 BindingDB Entry DOI: 10.7270/Q2542N8R
					More data for this Ligand-Target Pair				3D Structure (crystal)
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50131848 (CHEMBL3633532) Show SMILES N[C@@H](CSC1(c2cccc(Cl)c2)c2ccccc2CCc2ccccc12)C(O)=O |r| Show InChI InChI=1S/C24H22ClNO2S/c25-19-9-5-8-18(14-19)24(29-15-22(26)23(27)28)20-10-3-1-6-16(20)12-13-17-7-2-4-11-21(17)24/h1-11,14,22H,12-13,15,26H2,(H,27,28)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Binding affinity against delta opioid receptor in mouse hot plate test				ACS Med Chem Lett 6: 1004-9 (2015) Article DOI: 10.1021/acsmedchemlett.5b00221 BindingDB Entry DOI: 10.7270/Q2WM1G76
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50017772 (CHEMBL3288983) Show SMILES CC(C)(C)c1cccc(Nc2ccc3NC(=O)CCc3c2)c1 Show InChI InChI=1S/C19H22N2O/c1-19(2,3)14-5-4-6-15(12-14)20-16-8-9-17-13(11-16)7-10-18(22)21-17/h4-6,8-9,11-12,20H,7,10H2,1-3H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminal His-tagged KSP ATPase motor domain (unknown origin) expressed in bacteria incubated for 30 mins prior to ATP addition measur...				Bioorg Med Chem 22: 3171-9 (2014) Article DOI: 10.1016/j.bmc.2014.04.008 BindingDB Entry DOI: 10.7270/Q2ST7RD5
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM23823 ((2R)-2-amino-3-{[(4-methoxyphenyl)diphenylmethyl]s...) Show SMILES COc1ccc(cc1)C(SC[C@H](N)C(O)=O)(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C23H23NO3S/c1-27-20-14-12-19(13-15-20)23(17-8-4-2-5-9-17,18-10-6-3-7-11-18)28-16-21(24)22(25)26/h2-15,21H,16,24H2,1H3,(H,25,26)/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	166	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Binding affinity against delta opioid receptor in mouse hot plate test				ACS Med Chem Lett 6: 1004-9 (2015) Article DOI: 10.1021/acsmedchemlett.5b00221 BindingDB Entry DOI: 10.7270/Q2WM1G76
					More data for this Ligand-Target Pair				3D Structure (crystal)
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50347618 (CHEMBL1803022) Show SMILES FC(F)(F)c1ccc2c(c1)[nH]c1cc3[nH]ccc3cc21 Show InChI InChI=1S/C15H9F3N2/c16-15(17,18)9-1-2-10-11-5-8-3-4-19-12(8)7-14(11)20-13(10)6-9/h1-7,19-20H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assay				J Med Chem 54: 4839-46 (2011) Article DOI: 10.1021/jm200448n BindingDB Entry DOI: 10.7270/Q20V8D5G
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50347611 (CHEMBL1802991) Show SMILES FC(F)(F)c1ccc2c(c1)[nH]c1cc3CCC(=O)Nc3cc21 Show InChI InChI=1S/C16H11F3N2O/c17-16(18,19)9-2-3-10-11-7-12-8(1-4-15(22)21-12)5-13(11)20-14(10)6-9/h2-3,5-7,20H,1,4H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assay				J Med Chem 54: 4839-46 (2011) Article DOI: 10.1021/jm200448n BindingDB Entry DOI: 10.7270/Q20V8D5G
					More data for this Ligand-Target Pair

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