| Reaction Details |
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 | Report a problem with these data |
| Target | Serine protease 1 |
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| Ligand | BDBM50290999 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_212338 |
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| IC50 | 250±n/a nM |
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| Citation |  Semple, JE; Rowley, DC; Brunck, TK; Ripka, WC Synthesis and biological activity of P2–P4 azapeptidomimetic P1-argininal and P1-ketoargininamide derivatives: a novel class of serine protease inhibitors Bioorg Med Chem Lett7:315-320 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine protease 1 |
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| Name: | Serine protease 1 |
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| Synonyms: | Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I |
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| Type: | Enzyme |
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| Mol. Mass.: | 25790.52 |
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| Organism: | Bos taurus (bovine) |
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| Description: | P00760 |
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| Residue: | 246 |
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| Sequence: | MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVS
AAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLN
SRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQIT
SNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIK
QTIASN
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| BDBM50290999 |
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| n/a |
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| Name | BDBM50290999 |
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| Synonyms: | CHEMBL322034 | {N'-tert-Butoxycarbonyl-N-[2-(4-guanidino-1-phenethylaminooxalyl-butylcarbamoyl)-cyclohexanecarbonyl]-hydrazino}-acetic acid ethyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C32H49N7O8 |
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| Mol. Mass. | 659.7736 |
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| SMILES | CCOC(=O)CN(NC(=O)OC(C)(C)C)C(=O)[C@@H]1CCCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)C(=O)NCCc1ccccc1 |
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| Structure | 
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