| Reaction Details |
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 | Report a problem with these data |
| Target | Polyphenol oxidase 2 |
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| Ligand | BDBM50203065 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_618469 (CHEMBL1100455) |
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| IC50 | 520000±n/a nM |
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| Citation |  Ngoc, TM; Lee, I; Ha, do T; Kim, H; Min, B; Bae, K Tyrosinase-inhibitory constituents from the twigs of Cinnamomum cassia. J Nat Prod72:1205-8 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Polyphenol oxidase 2 |
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| Name: | Polyphenol oxidase 2 |
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| Synonyms: | Monophenol monooxygenase | Monophenol oxidase | PPO2 | PPO2_AGABI | Tyrosinase |
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| Type: | Protein |
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| Mol. Mass.: | 63923.66 |
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| Organism: | Agaricus bisporus (Common mushroom) |
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| Description: | O42713 |
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| Residue: | 556 |
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| Sequence: | MSLIATVGPTGGVKNRLNIVDFVKNEKFFTLYVRSLELLQAKEQHDYSSFFQLAGIHGLP
FTEWAKERPSMNLYKAGYCTHGQVLFPTWHRTYLSVLEQILQGAAIEVAKKFTSNQTDWV
QAAQDLRQPYWDWGFELMPPDEVIKNEEVNITNYDGKKISVKNPILRYHFHPIDPSFKPY
GDFATWRTTVRNPDRNRREDIPGLIKKMRLEEGQIREKTYNMLKFNDAWERFSNHGISDD
QHANSLESVHDDIHVMVGYGKIEGHMDHPFFAAFDPIFWLHHTNVDRLLSLWKAINPDVW
VTSGRNRDGTMGIAPNAQINSETPLEPFYQSGDKVWTSASLADTARLGYSYPDFDKLVGG
TKELIRDAIDDLIDERYGSKPSSGARNTAFDLLADFKGITKEHKEDLKMYDWTIHVAFKK
FELKESFSLLFYFASDGGDYDQENCFVGSINAFRGTAPETCANCQDNENLIQEGFIHLNH
YLARDLESFEPQDVHKFLKEKGLSYKLYSRGDKPLTSLSVKIEGRPLHLPPGEHRPKYDH
TQARVVFDDVAVHVIN
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| BDBM50203065 |
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| n/a |
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| Name | BDBM50203065 |
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| Synonyms: | 3-phenylacrylaldehyde | 3-phenylprop-2-enal | CHEMBL293492 | cinnamaldehyde | trans-cinnamaldehyde |
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| Type | Small organic molecule |
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| Emp. Form. | C9H8O |
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| Mol. Mass. | 132.1592 |
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| SMILES | O=C\C=C\c1ccccc1 |
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| Structure | 
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