| Reaction Details |
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 | Report a problem with these data |
| Target | Thymidine kinase, cytosolic |
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| Ligand | BDBM50317622 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_632888 (CHEMBL1107470) |
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| IC50 | 105000±n/a nM |
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| Citation |  Lin, J; Roy, V; Wang, L; You, L; Agrofoglio, LA; Deville-Bonne, D; McBrayer, TR; Coats, SJ; Schinazi, RF; Eriksson, S 3'-(1,2,3-Triazol-1-yl)-3'-deoxythymidine analogs as substrates for human and Ureaplasma parvum thymidine kinase for structure-activity investigations. Bioorg Med Chem18:3261-9 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Thymidine kinase, cytosolic |
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| Name: | Thymidine kinase, cytosolic |
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| Synonyms: | KITH_HUMAN | TK1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 25476.50 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1333884 |
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| Residue: | 234 |
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| Sequence: | MSCINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTR
YSSSFCTHDRNTMEALPACLLRDVAQEALGVAVIGIDEGQFFPDIVEFCEAMANAGKTVI
VAALDGTFQRKPFGAILNLVPLAESVVKLTAVCMECFREAAYTKRLGTEKEVEVIGGADK
YHSVCRLCYFKKASGQPAGPDNKENCPVPGKPGEAVAARKLFAPQQILQCSPAN
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| BDBM50317622 |
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| n/a |
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| Name | BDBM50317622 |
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| Synonyms: | 3'-(4-(3-Chloro-propyl)-1,2,3-triazol-1-yl)-3'-deoxythymidine | CHEMBL1098660 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H21N5O4 |
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| Mol. Mass. | 335.3583 |
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| SMILES | CCCc1cn(nn1)[C@H]1C[C@@H](O[C@@H]1CO)n1cc(C)c(=O)[nH]c1=O |r| |
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| Structure | 
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