| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor |
|---|
| Ligand | BDBM50049200 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_717451 (CHEMBL1670350) |
|---|
| Kd | 0.631±n/a nM |
|---|
| Citation |  Naik, P; Murumkar, P; Giridhar, R; Yadav, MR Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective. Bioorg Med Chem18:8418-56 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Type-1 angiotensin II receptor |
|---|
| Name: | Type-1 angiotensin II receptor |
|---|
| Synonyms: | AGTR1 | AGTR1_RABIT | ANGIOTENSIN AT1 | Angiotensin II receptor | Angiotensin II type 1a (AT-1a) receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 41009.15 |
|---|
| Organism: | RABBIT |
|---|
| Description: | ANGIOTENSIN AT1 AGTR1 RABBIT::P34976 |
|---|
| Residue: | 359 |
|---|
| Sequence: | MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE
|
|
|
|---|
| BDBM50049200 |
|---|
| n/a |
|---|
| Name | BDBM50049200 |
|---|
| Synonyms: | 2-Ethyl-5,7-dimethyl-3-[9-(1H-tetrazol-5-ylmethyl)-9H-fluoren-2-ylmethyl]-3H-imidazo[4,5-b]pyridine | CHEMBL433895 | KW-3433 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H25N7 |
|---|
| Mol. Mass. | 435.5236 |
|---|
| SMILES | CCc1nc2c(C)cc(C)nc2n1Cc1ccc-2c(c1)C(Cc1nnn[nH]1)c1ccccc-21 |
|---|
| Structure | 
|
|---|
Search and Browse
