| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Motilin receptor |
|---|
| Ligand | BDBM50299505 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_748951 (CHEMBL1781399) |
|---|
| EC50 | 260±n/a nM |
|---|
| Citation |  Liu, Y; Carreras, CW; Claypool, M; Myles, DC; Shaw, SJ The role of the 4''-hydroxyl on motilin agonist potency in the 9-dihydroerythromycin series. Bioorg Med Chem Lett21:3712-4 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Motilin receptor |
|---|
| Name: | Motilin receptor |
|---|
| Synonyms: | n/a |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 43771.25 |
|---|
| Organism: | Oryctolagus cuniculus |
|---|
| Description: | n/a |
|---|
| Residue: | 400 |
|---|
| Sequence: | MGSPWNGSDGPEDAREPPWAALPPCDERRCSPFPLGTLVPVTAVCLGLFAVGVSGNVVTV
LLIGRYRDMRTTTNLYLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGQLLCRLSLYVGEG
CTYASLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAALWAVALLSAGPFFFLVGVE
QDPAVFAAPDRNGTVPLDPSSPAPASPPSGPGAEAAALFSRECRPSRAQLGLLRVMLWVT
TAYFFLPFLCLSILYGLIARQLWRGRGPLRGPAATGRERGHRQTVRVLLVVVLAFIVCWL
PFHVGRIIYINTQDSRMMYFSQYFNIVALQLFYLSASINPILYNLISKKYRAAARRLLRE
SRAGPSGVCGSRGPEQDVAGDTGGDTAGCTETSANTKTAA
|
|
|
|---|
| BDBM50299505 |
|---|
| n/a |
|---|
| Name | BDBM50299505 |
|---|
| Synonyms: | 3 9-dihydro-N-desmethyl-N-isopropylerythromycin A | CHEMBL584549 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C39H73NO13 |
|---|
| Mol. Mass. | 763.9958 |
|---|
| SMILES | CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C(C)C)[C@](C)(O)C[C@@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@]1(C)O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
