| Reaction Details |
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 | Report a problem with these data |
| Target | Serine protease 1 |
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| Ligand | BDBM50291163 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_212354 |
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| IC50 | >1000000±n/a nM |
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| Citation |  Akiyama, Y; Tsutsumi, S; Hatsushiba, E; Ohuchi, S; Okonogi, T Peptidyl -keto thiazole as potent thrombin inhibitors Bioorg Med Chem Lett7:533-538 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine protease 1 |
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| Name: | Serine protease 1 |
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| Synonyms: | Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I |
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| Type: | Enzyme |
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| Mol. Mass.: | 25790.52 |
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| Organism: | Bos taurus (bovine) |
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| Description: | P00760 |
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| Residue: | 246 |
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| Sequence: | MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVS
AAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLN
SRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQIT
SNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIK
QTIASN
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| BDBM50291163 |
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| n/a |
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| Name | BDBM50291163 |
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| Synonyms: | 4-Phenyl-1-{(S)-2-[(R)-2-(thiazole-2-carbonyl)-pyrrolidine-1-carbonyl]-pyrrolidin-1-yl}-butan-1-one | CHEMBL436620 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H27N3O3S |
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| Mol. Mass. | 425.544 |
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| SMILES | O=C(CCCc1ccccc1)N1CCC[C@H]1C(=O)N1CCC[C@@H]1C(=O)c1nccs1 |
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| Structure | 
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