| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H2 receptor |
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| Ligand | BDBM50014888 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_85684 |
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| IC50 | 2500000±n/a nM |
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| Citation |  Martinez, J; Bali, JP; Magous, R; Laur, J; Lignon, MF; Briet, C; Nisato, D; Castro, B Structure-activity relationships of C-terminal tri- and tetrapeptide fragments that inhibit gastrin activity. J Med Chem28:273-8 (1985) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H2 receptor |
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| Name: | Histamine H2 receptor |
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| Synonyms: | Gastric receptor I | H2R | HISTAMINE H2 | HRH2_RAT | Hrh2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 40269.37 |
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| Organism: | RAT |
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| Description: | HISTAMINE H2 HRH2 RAT::P25102 |
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| Residue: | 358 |
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| Sequence: | MEPNGTVHSCCLDSMALKVTISVVLTTLILITIAGNVVVCLAVSLNRRLRSLTNCFIVSL
AATDLLLGLLVLPFSAIYQLSFTWSFGHVFCNIYTSLDVMLCTASILNLFMISLDRYCAV
TDPLRYPVLVTPVRVAISLVFIWVISITLSFLSIHLGWNSRNGTRGGNDTFKCKVQVNEV
YGLVDGLVTFYLPLLIMCVTYYRIFKIAREQAKRINHISSWKAATIREHKATVTLAAVMG
AFIICWFPYFTAFVYRGLRGDDAINEAVEGIVLWLGYANSALNPILYAALNRDFRTAYQQ
LFHCKFASHNSHKTSLRLNNSLLPRSQSREGRWQEEKPLKLQVWSGTELTHPQGNPIR
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| BDBM50014888 |
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| n/a |
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| Name | BDBM50014888 |
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| Synonyms: | 4-Benzoylamino-4-dipropylcarbamoyl-butyric acid | CHEMBL316561 | Proglumide |
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| Type | Small organic molecule |
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| Emp. Form. | C18H26N2O4 |
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| Mol. Mass. | 334.41 |
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| SMILES | CCCN(CCC)C(=O)C(CCC(O)=O)NC(=O)c1ccccc1 |
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| Structure | 
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