| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosylhomocysteinase |
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| Ligand | BDBM50019042 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_197369 |
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| IC50 | 80±n/a nM |
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| Citation |  Madhavan, GV; McGee, DP; Rydzewski, RM; Boehme, R; Martin, JC; Prisbe, EJ Synthesis and antiviral evaluation of 6'-substituted aristeromycins: potential mechanism-based inhibitors of S-adenosylhomocysteine hydrolase. J Med Chem31:1798-804 (1988) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosylhomocysteinase |
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| Name: | Adenosylhomocysteinase |
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| Synonyms: | AHCY | Adenosylhomocysteinase | SAHH | SAHH_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47714.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1507791 |
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| Residue: | 432 |
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| Sequence: | MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVET
AVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYF
KDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINV
NDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVI
ITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIG
HFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSN
SFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMS
CDGPFKPDHYRY
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| BDBM50019042 |
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| n/a |
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| Name | BDBM50019042 |
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| Synonyms: | 3-(6-Amino-purin-9-yl)-5-hydroxymethyl-4-methylene-cyclopentane-1,2-diol | CHEMBL53931 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H15N5O3 |
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| Mol. Mass. | 277.2792 |
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| SMILES | Nc1ncnc2n(cnc12)C1C(O)C(O)C(CO)C1=C |
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| Structure | 
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