| Reaction Details |
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 | Report a problem with these data |
| Target | Tubulin beta-2B chain |
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| Ligand | BDBM50044965 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_211332 (CHEMBL820775) |
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| IC50 | >40000±n/a nM |
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| Citation |  Kuo, SC; Lee, HZ; Juang, JP; Lin, YT; Wu, TS; Chang, JJ; Lednicer, D; Paull, KD; Lin, CM; Hamel, E Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin. J Med Chem36:1146-56 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Tubulin beta-2B chain |
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| Name: | Tubulin beta-2B chain |
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| Synonyms: | TBB2B_BOVIN | TUBB2B | Tubulin | Tubulin beta chain |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49932.38 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_211651 |
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| Residue: | 445 |
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| Sequence: | MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYV
PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV
RKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVV
EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM
AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG
LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
EYQQYQDATADEQGEFEEEEGEDEA
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| BDBM50044965 |
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| n/a |
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| Name | BDBM50044965 |
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| Synonyms: | 1-Methyl-2-phenyl-1H-quinolin-4-one | CHEMBL277048 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H13NO |
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| Mol. Mass. | 235.2805 |
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| SMILES | Cn1c(cc(=O)c2ccccc12)-c1ccccc1 |
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| Structure | 
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