| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M2 |
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| Ligand | BDBM50039199 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_140093 (CHEMBL752970) |
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| Ki | 1189±n/a nM |
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| Citation |  Calderon, SN; Izenwasser, S; Heller, B; Gutkind, JS; Mattson, MV; Su, TP; Newman, AH Novel 1-phenylcycloalkanecarboxylic acid derivatives are potent and selective sigma 1 ligands. J Med Chem37:2285-91 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M2 |
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| Name: | Muscarinic acetylcholine receptor M2 |
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| Synonyms: | ACM2_HUMAN | CHRM2 | Cholinergic, muscarinic M2 | Muscarinic acetylcholine receptor M2 and M4 | Muscarinic acetylcholine receptor M2 and M5 | RecName: Full=Muscarinic acetylcholine receptor M2 |
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| Type: | GPCR |
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| Mol. Mass.: | 51730.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08172 |
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| Residue: | 466 |
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| Sequence: | MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
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| BDBM50039199 |
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| n/a |
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| Name | BDBM50039199 |
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| Synonyms: | 1-(3,4-Dichloro-phenyl)-cyclohexanecarboxylic acid 2-morpholin-4-yl-ethoxymethyl ester | CHEMBL307628 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H27Cl2NO4 |
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| Mol. Mass. | 416.339 |
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| SMILES | Clc1ccc(cc1Cl)C1(CCCCC1)C(=O)OCOCCN1CCOCC1 |
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| Structure | 
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